HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.886

Property	Details
Experiments	27248496, 33961781, 18206970, 36765085
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106, Histone_H2A_C~Rtt106
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 1047
+	Hs
		1151400 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1185216 H2A3_HUMAN (1-130): 3.34e-68: 203: 99.23		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		470626 H2A1_HUMAN (1-130): 3.61e-68: 203: 98.46		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1087145 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1312248 H2AJ_HUMAN (1-126): 2.23e-65: 196: 94.44		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		555708 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Mm
		650195 H2AX_MOUSE (1-129): 7.47e-64: 192: 89.92		SP16H_MOUSE (1-1047): 0: 1332: 98.66
+	Sc
		392353 H2A2_YEAST (16-128): 1.02e-59: 181: 79.65		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Sc
		392084 H2A1_YEAST (16-127): 9.92e-53: 164: 80.36		SPT16_YEAST (3-1008): 0: 938: 33.49