HitPredict

Interactor 1: H2A1 (P04911)
Histone H2A.1
Gene: HTA1

Interactor 2: NHP6A (P11632)
Non-histone chromosomal protein 6A
Gene: NHP6A

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	29514976, 18448120
Identification Methods	pull down, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Sc			1 93
+	Hs
		594829 H2A1D_HUMAN (3-129): 1.53e-62: 189: 74.02		SOX2_HUMAN (13-92): 3.88e-31: 112: 27.50
+	Hs
		1151386 H2A2A_HUMAN (3-129): 8.55e-63: 189: 74.80		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		391917 H2A1B_HUMAN (3-129): 1.67e-62: 189: 74.02		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		470568 H2A1_HUMAN (3-129): 1.25e-62: 189: 74.80		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		1087107 H2A2C_HUMAN (3-130): 2.4e-62: 188: 73.44		HM20A_HUMAN (9-93): 1.03e-29: 109: 40.00
+	Hs
		996754 H2A2B_HUMAN (3-131): 2.08e-63: 191: 72.09		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		996856 H2A1J_HUMAN (3-129): 2.59e-63: 191: 74.02		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		391670 H2A1B_HUMAN (3-129): 1.67e-62: 189: 74.02		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		470362 H2A1_HUMAN (3-129): 1.25e-62: 189: 74.80		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		996711 H2A2A_HUMAN (3-129): 8.55e-63: 189: 74.80		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		996730 H2A3_HUMAN (3-129): 1.15e-62: 189: 74.80		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		996868 H2AJ_HUMAN (3-130): 7.26e-63: 189: 73.44		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Hs
		996693 H2A2C_HUMAN (3-130): 2.4e-62: 188: 73.44		SSRP1_HUMAN (1-89): 1.09e-26: 103: 37.36
+	Sc
		392263 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		NHP6A_YEAST (1-93): 4.36e-28: 98.8: 100.00
+	Sc
		392031 H2A1_YEAST (1-132): 2.22e-62: 188: 100.00		NHP6B_YEAST (2-93): 1.18e-25: 92.8: 86.96
+	Sc
		392264 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		NHP6B_YEAST (2-93): 1.18e-25: 92.8: 86.96
+	Hs
		449762 H2A2B_HUMAN (3-131): 2.08e-63: 191: 72.09		HMGB1_HUMAN (15-88): 6.83e-10: 55.1: 38.16
+	Hs
		449745 H2A2A_HUMAN (3-129): 8.55e-63: 189: 74.80		HMGB1_HUMAN (15-88): 6.83e-10: 55.1: 38.16
+	Hs
		643395 H2A1J_HUMAN (3-129): 2.59e-63: 191: 74.02		HMGB2_HUMAN (15-88): 5.31e-09: 52.4: 36.84
+	Hs
		643357 H2A2A_HUMAN (3-129): 8.55e-63: 189: 74.80		HMGB2_HUMAN (15-88): 5.31e-09: 52.4: 36.84