Protein: HSP90
Heat shock protein 90 homolog

Gene: HSP90
Organism: Candida albicans SC5314
Interactions: 116
UniProt ID: P46598

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

835802

HSP71
Heat shock protein HSP70

1

17

Small-scale

0.618

High

845371

CDK1
Cyclin-dependent kinase 1

1

13

Small-scale

0.618

High

857683

HSP90
Heat shock protein 90 homolog

1

15

High-throughput

0.618

High

857695

CLU
Clustered mitochondria protein homolog

1

2

High-throughput

0.618

High

857755

Q5ADP3
Transcription regulator

1

8

High-throughput

0.618

High

857768

Q5AJH3
Cyclin-dependent serine/threonine protein kinase

1

20

High-throughput

0.618

High

857778

Q5ANK2
Protein kinase C-like 1

1

20

Small-scale

0.618

High

857736

Q5A5P4
Tetratricopeptide repeat-containing protein

1

5

High-throughput

0.553

High

206083

1433
14-3-3 protein homolog

1

9

High-throughput

0.479

High

313516

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.479

High

313518

ADH2
Alcohol dehydrogenase 2

1

11

High-throughput

0.479

High

515423

TUP1
Transcriptional repressor TUP1

1

14

Small-scale

0.479

High

515426

EF1A1
Elongation factor 1-alpha 1

1

4

High-throughput

0.479

High

683578

EF3
Elongation factor 3

1

12

High-throughput

0.479

High

720824

ENO1
Enolase 1

1

8

High-throughput

0.479

High

857684

KPYK
Pyruvate kinase

1

5

High-throughput

0.479

High

857686

PMGY
Phosphoglycerate mutase

1

4

High-throughput

0.479

High

857687

ACH1
Acetyl-CoA hydrolase

1

3

High-throughput

0.479

High

857688

GBLP
Small ribosomal subunit protein RACK1

1

10

High-throughput

0.479

High

857689

MDHC
Malate dehydrogenase, cytoplasmic

1

8

High-throughput

0.479

High

857690

PDC1
Pyruvate decarboxylase

1

8

High-throughput

0.479

High

857691

VDAC
Mitochondrial outer membrane protein porin

1

5

High-throughput

0.479

High

857692

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

3

High-throughput

0.479

High

857693

IF4A
ATP-dependent RNA helicase eIF4A

1

7

High-throughput

0.479

High

857694

Q59M50
Cwt1p

1

4

Small-scale

0.479

High

857696

Q59NH3
Mitochondrial thiamine pyrophosphate carrier 1

1

5

High-throughput

0.479

High

857697

Q59P43
GTP-binding nuclear protein

1

6

High-throughput

0.479

High

857698

Q59P49
DNA replication licensing factor MCM5

1

9

High-throughput

0.479

High

857700

VATB
V-type proton ATPase subunit B

1

12

High-throughput

0.479

High

857701

Q59QB7
T-complex protein 1 subunit alpha

1

13

High-throughput

0.479

High

857702

Q59R18
asparagine--tRNA ligase

1

7

High-throughput

0.479

High

857703

Q59R20
proline--tRNA ligase

1

10

High-throughput

0.479

High

857704

Q59RI1
Isoleucine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.479

High

857705

Q59RQ6
Dihydrolipoyl dehydrogenase

1

4

High-throughput

0.479

High

857706

NOP58
Nucleolar protein 58

1

2

High-throughput

0.479

High

857707

Q59T95
Cystathionine beta-synthase

1

5

High-throughput

0.479

High

857709

Q59VX7
Importin-95

1

8

High-throughput

0.479

High

857710

GPD2
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2

1

5

High-throughput

0.479

High

857711

Q59WC5
4-nitrophenylphosphatase

1

2

High-throughput

0.479

High

857712

Q59WE2
E3 ubiquitin ligase complex SCF subunit

1

4

High-throughput

0.479

High

857714

Q59XU9
Glycerol-3-phosphate dehydrogenase [NAD(+)]

1

5

High-throughput

0.479

High

857715

Q59XW4
Acetyl-coenzyme A synthetase

1

5

High-throughput

0.479

High

857717

Q59YH4
T-complex protein 1 subunit eta

1

13

High-throughput

0.479

High

857719

Q59Z11
Actin-related protein 3

1

8

High-throughput

0.479

High

857720

Q59Z12
T-complex protein 1 subunit epsilon

1

13

High-throughput

0.479

High

857721

Q59ZH8
Translation termination factor eRF1

1

2

High-throughput

0.479

High

857722

XPOT
Exportin-T

1

7

High-throughput

0.479

High

857724

Q5A0L8
26S proteasome regulatory subunit 6B homolog

1

6

High-throughput

0.479

High

857725

EF2
Elongation factor 2

1

8

High-throughput

0.479

High

857726

Q5A0N3
Ribonucleoside-diphosphate reductase

1

2

High-throughput

0.479

High

857728

RUVB1
RuvB-like helicase 1

1

8

High-throughput

0.479

High

857729

Q5A2A0
26S proteasome regulatory subunit 7 homolog

1

7

High-throughput

0.479

High

857730

Q5A2U9
V-type proton ATPase subunit C

1

2

High-throughput

0.479

High

857734

Q5A4W7
Fatty acid synthase subunit beta

1

3

High-throughput

0.479

High

857735

Q5A516
ADP/ATP translocase

1

4

High-throughput

0.479

High

857738

Q5A6M6
Coatomer subunit beta

1

2

High-throughput

0.479

High

857739

Q5A6P9
Adenylyl cyclase-associated protein

1

4

High-throughput

0.479

High

857740

Q5A6S2
Proteasome regulatory particle base subunit

1

11

High-throughput

0.479

High

857741

SDS24
Protein SDS23

1

5

High-throughput

0.479

High

857742

Q5A750
Transketolase

1

6

High-throughput

0.479

High

857743

Q5A779
GTP-binding protein

1

9

High-throughput

0.479

High

857744

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

857746

Q5A850
Glycogen [starch] synthase

1

3

High-throughput

0.479

High

857747

Q5A8Y5
DNA-directed RNA polymerase subunit beta

1

4

High-throughput

0.479

High

857749

DHH1
ATP-dependent RNA helicase DHH1

1

5

High-throughput

0.479

High

857750

Q5AB74
CCT-theta

1

9

High-throughput

0.479

High

857751

Q5ABC3
Elongation factor Tu

1

8

High-throughput

0.479

High

857752

PPID
Peptidyl-prolyl cis-trans isomerase D

1

11

High-throughput

0.479

High

857753

Q5ADM7
Glyceraldehyde-3-phosphate dehydrogenase

1

8

High-throughput

0.479

High

857754

Q5ADN1
Protein phosphatase 2A structural subunit

1

4

High-throughput

0.479

High

857756

Q5ADR6
Translation initiation factor eIF2B subunit delta

1

6

High-throughput

0.479

High

857759

RV161
Regulator of cytoskeleton and endocytosis RVS161

1

4

High-throughput

0.479

High

857762

Q5AGZ8
ATP-dependent 6-phosphofructokinase

1

5

High-throughput

0.479

High

857763

RUVB2
RuvB-like helicase 2

1

8

High-throughput

0.479

High

857767

DBP5
ATP-dependent RNA helicase DBP5

1

4

High-throughput

0.479

High

857769

Q5AJX7
PH domain-containing protein

1

5

High-throughput

0.479

High

857771

Q5AK16
T-complex protein 1 subunit gamma

1

9

High-throughput

0.479

High

857772

Q5AK53
ATP-dependent 6-phosphofructokinase

1

5

High-throughput

0.479

High

857773

Q5AKW2
Myosin 2

1

9

High-throughput

0.479

High

857775

Q5ALK3
ribose-phosphate diphosphokinase

1

5

High-throughput

0.479

High

857777

BGL2
Glucan 1,3-beta-glucosidase BGL2

1

2

High-throughput

0.479

High

857779

Q5AP79
Mitochondrial thiamine pyrophosphate carrier 1

1

11

High-throughput

0.479

High

857780

WOR1
White-opaque regulator 1

1

2

Small-scale

0.479

High

857781

DBP3
ATP-dependent RNA helicase DBP3

1

4

High-throughput

0.479

High

857782

HSF
Heat shock transcription factor

1

10

Small-scale

0.479

High

857783

ACS2
Acetyl-coenzyme A synthetase 2

1

5

High-throughput

0.479

High

857785

ALF
Fructose-bisphosphate aldolase

1

2

High-throughput

0.479

High

857787

MET3
Sulfate adenylyltransferase

1

2

High-throughput

0.479

High

857713

Q59WV8
Uncharacterized protein

1

0

High-throughput

0.458

High

857731

RMD9
RNA-binding protein RMD9, mitochondrial

1

0

High-throughput

0.458

High

857745

Q5A7M2
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.458

High

857748

Q5A8Z9
Mitochondrial outer membrane protein OM14 C-terminal domain-containing protein

1

0

High-throughput

0.458

High

857765

HSP21
Small heat shock protein 21

1

0

High-throughput

0.458

High

857774

Q5AKZ4
Mcu1p

1

0

Small-scale

0.458

High

515416

HAL21
3'(2'),5'-bisphosphate nucleotidase 1

1

3

High-throughput

0.437

High

857685

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

6

High-throughput

0.437

High

857699

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

8

High-throughput

0.437

High

857708

Q59TC4
homocitrate synthase

1

8

High-throughput

0.437

High

857716

Q59YE8
Eukaryotic peptide chain release factor GTP-binding subunit

1

7

High-throughput

0.437

High

857718

ESF2
Pre-rRNA-processing protein ESF2

1

2

High-throughput

0.437

High

857723

Q5A0L0
Ribonucleotide-diphosphate reductase subunit

1

6

High-throughput

0.437

High

857727

GPN3
GPN-loop GTPase 3

1

3

High-throughput

0.437

High

857732

Q5A3L0
26S proteasome regulatory subunit RPN2

1

6

High-throughput

0.437

High

857733

Q5A462
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.437

High

857737

Q5A5Q8
40S ribosomal protein S4

1

3

High-throughput

0.437

High

857757

Q5AEB5
Ulp1p

1

4

High-throughput

0.437

High

857758

MED7
Mediator of RNA polymerase II transcription subunit 7

1

2

Small-scale

0.437

High

857760

Q5AG96
JAB1/MPN/MOV34 metalloenzyme domain-containing protein

1

11

High-throughput

0.437

High

857761

Q5AGF6
Eukaryotic translation initiation factor 2 subunit gamma

1

12

High-throughput

0.437

High

857766

Q5AIA2
Homoserine dehydrogenase

1

2

High-throughput

0.437

High

857776

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

3

High-throughput

0.437

High

857784

RLA1
Large ribosomal subunit protein P1A

1

2

High-throughput

0.437

High

857786

RL10A
Large ribosomal subunit protein uL1

1

5

High-throughput

0.437

High

857764

Q5AH76
C2 NT-type domain-containing protein

1

0

High-throughput

0.249

Low

857770

Q5AK00
RRM domain-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025