HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.80	0.731

Property	Details
Experiments	18158899, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 978
+	Sc
		392015 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		SIR3_YEAST (1-978): 0: 937: 100.00
+	Sc
		392528 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		ORC1_YEAST (1-975): 0: 754: 23.77
+	Sc
		392178 H2A1_YEAST (1-132): 2.35e-62: 188: 98.49		ORC1_YEAST (1-975): 0: 754: 23.77
+	Hs
		1033386 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		ORC1_HUMAN (179-959): 3.67e-175: 533: 13.85
+	Hs
		391577 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		RFC1_HUMAN (129-771): 6.79e-26: 117: 12.24
+	Sc
		392530 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		ORC4_YEAST (490-896): 8.62e-16: 83.5: 8.37
+	Sc
		392415 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RFC1_YEAST (265-769): 2.54e-14: 79.7: 10.46