HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19106085, 19661920
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031298 - replication fork protection complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Sc			1 933
+	Hs
		832655 H2A1A_HUMAN (3-130): 1.25e-64: 194: 74.22		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832672 H2A1J_HUMAN (3-128): 1.79e-63: 191: 74.60		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832567 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832648 H2A1H_HUMAN (3-128): 3.42e-63: 190: 75.40		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832683 H2AJ_HUMAN (3-130): 3.28e-63: 190: 73.44		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		594831 H2A1D_HUMAN (3-128): 1.18e-62: 189: 74.60		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832548 H2A3_HUMAN (3-128): 9.58e-63: 189: 75.40		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		832623 H2A1C_HUMAN (3-128): 8.4e-63: 189: 76.19		MCM2_HUMAN (31-902): 0: 714: 26.03
+	Hs
		708736 H2A1A_HUMAN (3-130): 1.25e-64: 194: 74.22		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708748 H2A1J_HUMAN (3-128): 1.79e-63: 191: 74.60		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708697 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708733 H2A1H_HUMAN (3-128): 3.42e-63: 190: 75.40		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708755 H2AJ_HUMAN (3-130): 3.28e-63: 190: 73.44		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		594826 H2A1D_HUMAN (3-128): 1.18e-62: 189: 74.60		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708663 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708693 H2A3_HUMAN (3-128): 9.58e-63: 189: 75.40		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Hs
		708718 H2A1C_HUMAN (3-128): 8.4e-63: 189: 76.19		MCM5_HUMAN (155-909): 0: 703: 28.42
+	Sc
		392334 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		MCM5_YEAST (189-905): 0: 679: 26.92
+	Sc
		392333 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		MCM2_YEAST (23-849): 0: 677: 25.49
+	Sc
		392402 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		MCM7_YEAST (314-863): 6.73e-96: 322: 39.04