Protein: NSR1
Nuclear localization sequence-binding protein (p67)

Gene: NSR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 174
UniProt ID: P27476

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

692556

NOP4
Nucleolar protein 4

2

20

High-throughput

0.767

High

434881

RS3
Small ribosomal subunit protein uS3

2

3

High-throughput

0.737

High

585221

FBRL
rRNA 2'-O-methyltransferase fibrillarin

4

1

Small-scale

0.693

High

692539

XPO1
Exportin-1

1

7

High-throughput

0.691

High

692542

HOG1
Mitogen-activated protein kinase HOG1

1

12

High-throughput

0.691

High

692552

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

1

High-throughput

0.691

High

403385

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

18

High-throughput

0.665

High

692534

NSR1
Nuclear localization sequence-binding protein

1

18

High-throughput

0.665

High

692608

NOP3
Serine/arginine

1

20

Small-scale

0.656

High

441056

KAPA
cAMP-dependent protein kinase type 1

1

13

High-throughput

0.647

High

517928

SSBP1
Single-stranded nucleic acid-binding protein

1

19

High-throughput

0.647

High

656379

KC11
Casein kinase I homolog 1

1

7

High-throughput

0.647

High

656708

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.647

High

692545

SWE1
Mitosis inhibitor protein kinase SWE1

1

16

High-throughput

0.647

High

692583

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

7

High-throughput

0.647

High

692615

STE20
Serine/threonine-protein kinase STE20

1

6

High-throughput

0.647

High

415205

TOP1
DNA topoisomerase 1

3

1

Small-scale

0.646

High

523232

HSP71
Heat shock protein SSA1

3

5

High-throughput

0.633

High

692649

NOP56
Nucleolar protein 56

2

2

High-throughput

0.628

High

544023

SSB1
Ribosome-associated molecular chaperone SSB1

3

9

High-throughput

0.624

High

364375

CDK1
Cyclin-dependent kinase 1

1

7

High-throughput

0.618

High

409973

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.618

High

644878

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.618

High

647026

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.618

High

676890

SRO9
RNA-binding protein SRO9

1

20

High-throughput

0.618

High

692602

NOP15
Ribosome biogenesis protein 15

1

20

High-throughput

0.618

High

692626

MRD1
Multiple RNA-binding domain-containing protein 1

1

18

High-throughput

0.618

High

692641

NCBP2
Nuclear cap-binding protein subunit 2

1

20

High-throughput

0.618

High

692596

PXR1
Protein PXR1

2

2

High-throughput

0.614

High

666407

DBP2
ATP-dependent RNA helicase DBP2

2

11

High-throughput

0.613

High

692601

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

1

Small-scale

0.606

High

692558

ANM1
Protein arginine N-methyltransferase 1

2

9

Small-scale

0.602

High

632534

DBP3
ATP-dependent RNA helicase DBP3

2

14

High-throughput

0.601

High

670406

SIS1
Protein SIS1

2

3

High-throughput

0.601

High

692547

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

3

High-throughput

0.601

High

692590

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

6

High-throughput

0.601

High

692650

NOP58
Nucleolar protein 58

2

2

High-throughput

0.601

High

692582

NOP9
Nucleolar protein 9

2

0

Small-scale

0.585

High

392336

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.584

High

578959

HSC82
ATP-dependent molecular chaperone HSC82

2

7

High-throughput

0.584

High

692540

HS104
Heat shock protein 104

2

3

High-throughput

0.584

High

692576

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.584

High

649573

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.579

High

692295

KCC1
Calcium/calmodulin-dependent protein kinase I

1

3

High-throughput

0.579

High

692559

AKL1
Serine/threonine-protein kinase AKL1

1

2

High-throughput

0.579

High

692589

ATG1
Serine/threonine-protein kinase ATG1

1

4

High-throughput

0.579

High

645312

XRN1
5'-3' exoribonuclease 1

2

7

High-throughput

0.571

High

689304

RS7A
Small ribosomal subunit protein eS7A

2

1

High-throughput

0.571

High

692544

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.571

High

692557

GBLP
Small ribosomal subunit protein RACK1

2

7

High-throughput

0.571

High

692622

RRP5
rRNA biogenesis protein RRP5

2

11

High-throughput

0.571

High

692579

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

0

High-throughput

0.569

High

692561

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

692652

EFG1P
rRNA-processing protein EFG1

2

0

Small-scale

0.559

High

692536

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

2

High-throughput

0.541

High

454417

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.536

High

692606

SEN1
Helicase SEN1

1

16

Small-scale

0.536

High

692607

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

9

High-throughput

0.536

High

692599

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.518

High

444442

DED1
ATP-dependent RNA helicase DED1

1

13

High-throughput

0.515

High

478593

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

2

High-throughput

0.515

High

676608

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.513

High

692571

RV167
Reduced viability upon starvation protein 167

1

9

High-throughput

0.494

High

149626

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

383558

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

419629

H2A2
Histone H2A.2

1

7

High-throughput

0.479

High

433492

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

435816

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

441748

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

454919

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

512299

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

514496

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

594231

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

674458

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

677308

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

678510

TAH1
TPR repeat-containing protein associated with Hsp90

1

3

Small-scale

0.479

High

679439

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

682182

SPB4
ATP-dependent rRNA helicase SPB4

1

18

High-throughput

0.479

High

692537

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

692538

TF3B
Transcription factor IIIB 70 kDa subunit

1

4

High-throughput

0.479

High

692541

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

692543

SRP40
Suppressor protein SRP40

1

1

High-throughput

0.479

High

692546

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

692550

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

Small-scale

0.479

High

692551

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

692555

LONM
Lon protease homolog, mitochondrial

1

8

High-throughput

0.479

High

692562

RS20
Small ribosomal subunit protein uS10

1

5

High-throughput

0.479

High

692574

MLP2
Protein MLP2

1

11

High-throughput

0.479

High

692577

RLP7
Ribosome biogenesis protein RLP7

1

7

High-throughput

0.479

High

692578

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

692581

NET1
Nucleolar protein NET1

1

1

High-throughput

0.479

High

692584

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

692585

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

692592

NMA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

1

High-throughput

0.479

High

692593

EIF2A
Eukaryotic translation initiation factor 2A

1

4

High-throughput

0.479

High

692594

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

692600

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

9

High-throughput

0.479

High

692603

SAM50
Sorting assembly machinery 50 kDa subunit

1

3

High-throughput

0.479

High

692604

ORC1
Origin recognition complex subunit 1

1

6

High-throughput

0.479

High

692605

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.479

High

692609

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

692610

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.479

High

692611

XRN2
5'-3' exoribonuclease 2

1

7

High-throughput

0.479

High

692612

NOG1
Nucleolar GTP-binding protein 1

1

4

High-throughput

0.479

High

692613

HOT1
High-osmolarity-induced transcription protein 1

1

1

Small-scale

0.479

High

692614

TOM1
E3 ubiquitin-protein ligase TOM1

1

10

High-throughput

0.479

High

692616

FIN1
Filament protein FIN1

1

1

Small-scale

0.479

High

692618

DHR1
Probable ATP-dependent RNA helicase DHR1

1

12

High-throughput

0.479

High

692624

HRQ1
ATP-dependent helicase HRQ1

1

20

Small-scale

0.479

High

692625

UTP21
U3 small nucleolar RNA-associated protein 21

1

3

Small-scale

0.479

High

692627

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

692628

NMA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

1

High-throughput

0.479

High

692629

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

692630

ESF1
Pre-rRNA-processing protein ESF1

1

1

Small-scale

0.479

High

692631

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

692632

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

15

Small-scale

0.479

High

692635

TSR1
Ribosome biogenesis protein TSR1

1

1

High-throughput

0.479

High

692636

BRE1
E3 ubiquitin-protein ligase BRE1

1

7

Small-scale

0.479

High

692638

SGO1
Shugoshin

1

1

High-throughput

0.479

High

692639

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

692640

VTS1
RNA-binding protein VTS1

1

1

High-throughput

0.479

High

692643

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

10

High-throughput

0.479

High

692644

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.479

High

692645

MAK21
Ribosome biogenesis protein MAK21

1

3

High-throughput

0.479

High

692646

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

692648

DBP10
ATP-dependent RNA helicase DBP10

1

20

High-throughput

0.479

High

692651

SMC6
Structural maintenance of chromosomes protein 6

1

7

High-throughput

0.479

High

692634

LEC1
PX domain-containing protein LEC1

1

0

Small-scale

0.460

High

692549

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.458

High

692553

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

692565

YHP7
Uncharacterized protein YHR097C

1

0

High-throughput

0.458

High

692568

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

692575

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

692619

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

692637

RTC1
Restriction of telomere capping protein 1

1

5

High-throughput

0.457

High

394299

EF1A
Elongation factor 1-alpha

1

12

High-throughput

0.445

High

511745

RS24A
Small ribosomal subunit protein eS24A

1

2

High-throughput

0.445

High

684645

RL5
Large ribosomal subunit protein uL18

1

5

High-throughput

0.445

High

688833

RS5
Small ribosomal subunit protein uS7

1

1

High-throughput

0.445

High

692554

RPF2
Ribosome biogenesis protein RPF2

1

1

High-throughput

0.445

High

692564

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

692573

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

692588

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

4

High-throughput

0.445

High

692598

BRE5
UBP3-associated protein BRE5

1

14

High-throughput

0.445

High

692642

HFI1
SAGA complex subunit HFI1

1

1

High-throughput

0.445

High

502889

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

504075

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

512861

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

558612

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

602070

SAC7
GTPase-activating protein SAC7

1

3

High-throughput

0.437

High

692535

CBPS
Carboxypeptidase S

1

1

High-throughput

0.437

High

692548

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

692569

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

692580

ALY2
Arrestin-related trafficking adapter 3

1

2

High-throughput

0.437

High

692586

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

692587

YG51
Uncharacterized protein YGR237C

1

1

High-throughput

0.437

High

692597

COPA
Coatomer subunit alpha

1

2

High-throughput

0.437

High

692620

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

692633

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.437

High

692567

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

692595

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.426

High

692617

PPN1
Endopolyphosphatase

1

0

High-throughput

0.426

High

692623

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

692563

NPR3
Nitrogen permease regulator 3

1

1

High-throughput

0.407

High

692570

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

5

High-throughput

0.407

High

692572

NPR2
Nitrogen permease regulator 2

1

1

High-throughput

0.407

High

692647

HSP42
Heat shock protein 42

1

3

High-throughput

0.407

High

692591

ERV14
ER-derived vesicles protein ERV14

1

0

High-throughput

0.249

Low

427163

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

671583

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

692560

SEA4
SEH-associated protein 4

1

0

High-throughput

0.232

Low

692566

ECM14
Inactive metallocarboxypeptidase ECM14

1

0

High-throughput

0.232

Low

692621

SNO4
Probable glutathione-independent glyoxalase SNO4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025