HitPredict

Interactor 1: AT1A1 (P05023)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: ATP1A1

Interactor 2: AT1A2 (P50993)
Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2)
Gene: ATP1A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34349018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase~E1-E2_ATPase, Cation_ATPase_C~Cation_ATPase_C, Cation_ATPase_C~E1-E2_ATPase, Cation_ATPase_C~Hydrolase, Cation_ATPase_N~E1-E2_ATPase, Cation_ATPase_N~Hydrolase, E1-E2_ATPase~E1-E2_ATPase, E1-E2_ATPase~Hydrolase
Common GO terms GO:0002026 - regulation of the force of heart contraction
GO:0005391 - P-type sodium:potassium-exchanging transporter activity
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
and 25 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1023
Hs

1 1020
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Last updated: 15 Jul 2024