HitPredict

Interactor 1: AT1A1 (P05023)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: ATP1A1

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1023 Hs			1 258
+	Hs
		392986 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		393129 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		393158 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		393152 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		393146 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		393135 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		393014 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		393131 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		393020 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		393348 AT1A1_HUMAN (1-1023): 0: 1139: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26
+	Hs
		530865 AT1A3_HUMAN (26-1023): 0: 1085: 87.88		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Dm
		185470 ATNA_DROME (17-1023): 0: 1050: 75.87		O18332_DROME (39-256): 1.05e-80: 242: 22.37
+	Hs
		594732 ATP4A_HUMAN (32-1023): 0: 982: 63.95		RAB1A_HUMAN (39-256): 5.65e-82: 246: 21.92
+	Hs
		594731 ATP4A_HUMAN (32-1023): 0: 982: 63.95		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		561551 AT2A2_HUMAN (42-1012): 0: 779: 26.90		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		561542 AT2A2_HUMAN (42-1012): 0: 779: 26.90		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Dm
		185471 ATC1_DROME (42-837): 2.46e-111: 370: 32.05		O18332_DROME (39-256): 1.05e-80: 242: 22.37
+	Hs
		900378 AT2C1_HUMAN (45-880): 3.62e-114: 376: 31.46		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		958320 AT2C1_HUMAN (45-880): 3.62e-114: 376: 31.46		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26