Protein: ROT1
Protein ROT1 (Reversal of TOR2 lethality protein 1)

Gene: ROT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 19
UniProt ID: Q03691

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006457 - protein folding
GO:0006458 - 'de novo' protein folding
GO:0006487 - protein N-linked glycosylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597260

BIP
Endoplasmic reticulum chaperone BiP

2

0

Small-scale

0.559

High

737991

KRE6
Beta-glucan synthesis-associated protein KRE6

2

0

Small-scale

0.559

High

805251

BIG1
Protein BIG1

1

0

Small-scale

0.458

High

873144

OST3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

1

0

Small-scale

0.458

High

393254

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

525001

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527561

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

579981

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

742292

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

510783

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

546099

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

671068

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

811382

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

863713

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

449176

CALM
Calmodulin

1

0

Small-scale

0.292

High

1043618

SFM1
Protein arginine N-methyltransferase SFM1

1

0

High-throughput

0.269

Low

877893

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

736718

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.238

Low

752674

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025