HitPredict

Interactor 1: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 10497223, 11932255, 19843520, 11412103, 35044719, 16546176
Identification Methods unspecified method, pull down, enzyme linked immunosorbent assay, affinity technology, saturation binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007044 - cell-substrate junction assembly
GO:0007229 - integrin-mediated signaling pathway
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 788
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024