Protein: NELFB
Negative elongation factor B (NELF-B) (Cofactor of BRCA1)

Gene: NELFB
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q8WX92

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0008283 - cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1312156

NELFD
Negative elongation factor C/D

8

1

Small-scale

0.972

High

615575

NELFE
Negative elongation factor E

13

1

Small-scale

0.762

High

1360069

NELFA
Negative elongation factor A

7

1

Small-scale

0.748

High

730098

1433B
14-3-3 protein beta/alpha

3

5

High-throughput

0.675

High

621923

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.656

High

966676

1433G
14-3-3 protein gamma

2

5

High-throughput

0.628

High

990546

1433Z
14-3-3 protein zeta/delta

2

5

High-throughput

0.628

High

430171

JUN
Transcription factor Jun

2

1

Small-scale

0.619

High

971832

1433E
14-3-3 protein epsilon

2

0

High-throughput

0.602

High

130557

SPT5H
Transcription elongation factor SPT5

2

0

Small-scale

0.585

High

260221

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

998601

H31
Histone H3.1

2

1

High-throughput

0.584

High

1330655

TPRX1
Tetra-peptide repeat homeobox protein 1

2

0

High-throughput

0.580

High

1066726

NCBP1
Nuclear cap-binding protein subunit 1

2

0

High-throughput

0.576

High

799333

BRCA1
Breast cancer type 1 susceptibility protein

1

0

Small-scale

0.561

High

370737

FOS
Protein c-Fos

1

1

Small-scale

0.561

High

396601

ESR1
Estrogen receptor

1

1

Small-scale

0.561

High

242424

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

220704

DENR
Density-regulated protein

1

0

High-throughput

0.554

High

284703

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

0

High-throughput

0.554

High

801431

HSPA9
Stress-70 protein, mitochondrial

1

0

High-throughput

0.554

High

1157014

NTRK3
NT-3 growth factor receptor

1

1

Small-scale

0.552

High

1152987

CEBPE
CCAAT/enhancer-binding protein epsilon

1

1

High-throughput

0.541

High

691286

1433T
14-3-3 protein theta

1

5

High-throughput

0.536

High

1049614

1433F
14-3-3 protein eta

1

5

High-throughput

0.536

High

911644

NCBP2
Nuclear cap-binding protein subunit 2

2

0

High-throughput

0.528

High

1055948

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.518

High

388260

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

445228

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

621693

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.513

High

723030

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

787764

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

904435

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.513

High

912094

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.513

High

912207

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.513

High

923516

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

959011

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

994314

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.513

High

1030481

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.513

High

1061072

SRSF1
Serine/arginine-rich splicing factor 1

1

0

High-throughput

0.513

High

1065323

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1360071

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1360072

INT9
Integrator complex subunit 9

1

0

High-throughput

0.513

High

1161164

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.508

High

362329

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.479

High

440652

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.479

High

594060

NCK1
SH2/SH3 adapter protein NCK1

1

3

High-throughput

0.479

High

987802

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.479

High

1017062

H33
Histone H3.3

1

1

High-throughput

0.479

High

1201951

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

1360060

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

132185

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

243688

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

0

High-throughput

0.458

High

315817

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

417628

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

589268

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

619084

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.458

High

667381

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

696054

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

699812

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.458

High

731503

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

768754

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

800009

COIL
Coilin

1

0

High-throughput

0.458

High

846641

MSH2
DNA mismatch repair protein Msh2

1

0

High-throughput

0.458

High

899153

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.458

High

906126

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.458

High

1004894

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1029881

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1088928

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1100172

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1138437

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1220694

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1254831

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1258351

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

1276551

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1360061

P33MX
Putative monooxygenase p33MONOX

1

0

Small-scale

0.458

High

1360065

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1360066

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

0

High-throughput

0.458

High

1360067

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.458

High

1360068

TCAL2
Transcription elongation factor A protein-like 2

1

0

High-throughput

0.458

High

1360073

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1360074

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

1360076

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

412331

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

1227156

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1111142

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1209449

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1360063

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

887055

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

592947

ANK1
Ankyrin-1

2

0

High-throughput

0.328

High

653468

HEMH
Ferrochelatase, mitochondrial

2

0

High-throughput

0.328

High

528775

MGST1
Microsomal glutathione S-transferase 1

1

0

High-throughput

0.301

High

762246

TRY3
Trypsin-3

1

0

High-throughput

0.279

Low

1294666

XYLT1
Xylosyltransferase 1

1

0

High-throughput

0.279

Low

1360064

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.279

Low

1360075

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

106353

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

420637

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.249

Low

1331228

ARL10
ADP-ribosylation factor-like protein 10

1

0

High-throughput

0.249

Low

1360070

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

1360062

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025