HitPredict

Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 769 Hs			1 416
+	Hs
		112057 L7RT22_HUMAN (23-760): 0: 635: 37.52		K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69
+	Hs
		574546 ITB5_HUMAN (23-760): 0: 635: 37.52		K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69
+	Hs
		556457 ITB4_HUMAN (1-700): 0: 588: 33.47		K1C40_HUMAN (6-385): 2.22e-144: 419: 62.69
+	Hs
		574540 ITB5_HUMAN (23-760): 0: 635: 37.52		K1H1_HUMAN (1-416): 1.18e-87: 273: 100.00
+	Hs
		280523 ITB5_HUMAN (23-760): 0: 635: 37.52		KRT34_HUMAN (1-390): 5.34e-79: 251: 89.23
+	Hs
		556445 ITB4_HUMAN (1-700): 0: 588: 33.47		K1H1_HUMAN (1-416): 1.18e-87: 273: 100.00
+	Hs
		631078 LAMA1_HUMAN (510-710): 1.43e-10: 67.4: 13.62		KRT35_HUMAN (2-411): 6.51e-83: 263: 71.46