HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15642721
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0006954 - inflammatory response and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 192
+	Hs
		416397 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		380763 S100B_HUMAN (2-89): 3.95e-27: 96.4: 32.61		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		396675 S10A8_HUMAN (1-93): 2.17e-30: 104: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		416345 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		642929 S10A4_HUMAN (1-93): 4.07e-31: 106: 27.84		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		661224 S10A2_HUMAN (1-92): 1.72e-29: 102: 26.04		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		416391 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31