Interactor 1: KPCG (P05129)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: PRKCG

Interactor 2: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 28514442, 31980649, 33961781, 32707033, unassigned2173
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~C2, C1_1~Pkinase, C2~C2, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0004698 - calcium,diacylglycerol-dependent serine/threonine kinase activity
GO:0005524 - ATP binding
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 697
Hs

1 672
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Last updated: 15 Jul 2024