HitPredict

Interactor 1: IC1 (P05155)
Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1)
Gene: SERPING1

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	35156780
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 500 Hs			1 1480
+	Hs
		344270 AACT_HUMAN (117-499): 2.88e-143: 419: 26.55		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		344156 A1AT_HUMAN (106-498): 9.39e-142: 415: 24.69		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		344101 ANT3_HUMAN (101-498): 5.59e-138: 407: 23.56		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528758 SPB10_HUMAN (141-498): 2.29e-135: 398: 24.81		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528609 SPB3_HUMAN (140-498): 5.67e-134: 394: 24.37		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528610 KAIN_HUMAN (137-498): 4.28e-127: 378: 22.92		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529588 SPB12_HUMAN (141-498): 4.46e-125: 372: 23.89		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		397088 PAI1_HUMAN (136-498): 2.46e-122: 365: 23.56		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		403563 HEP2_HUMAN (149-498): 8.11e-21: 97.1: 23.93		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		179386 AACT_HUMAN (117-499): 2.88e-143: 419: 26.55		MRP5_HUMAN (774-1479): 5.77e-53: 207: 13.26
+	Hs
		839495 SPB8_HUMAN (142-498): 5.85e-141: 411: 27.39		ABCA9_HUMAN (75-736): 2.05e-40: 166: 9.96