HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	33024031, 34599178
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 285
+	Hs
		433112 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		LAMB1_HUMAN (7-281): 2.34e-53: 188: 21.56
+	Hs
		475882 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		FKB15_HUMAN (1-284): 5.16e-27: 112: 13.40
+	Hs
		397736 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20
+	Mm
		476685 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		LAMA1_MOUSE (4-280): 3.27e-51: 182: 14.84
+	Hs
		397728 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27
+	Hs
		397899 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96
+	Rn
		387972 UBC_RAT (2-110): 2.29e-33: 125: 28.44		TPM1_RAT (2-285): 2.33e-44: 153: 91.55
+	Rn
		1144153 UBC_RAT (2-110): 2.29e-33: 125: 28.44		TPM3_RAT (41-285): 5.68e-36: 130: 71.43