Protein: NU4M
NADH-ubiquinone oxidoreductase chain 4 (EC 7.1.1.2) (NADH dehydrogenase subunit 4)

Gene: NU4M, MT-ND4
Organism: Homo sapiens
Interactions: 68
UniProt ID: P03905

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001701 - in utero embryonic development
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

223593

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

2

2

High-throughput

0.811

High

231194

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

2

1

High-throughput

0.811

High

397711

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

2

2

High-throughput

0.811

High

333545

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

2

2

High-throughput

0.776

High

223693

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

2

High-throughput

0.691

High

397662

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

1

1

High-throughput

0.691

High

278608

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

3

2

High-throughput

0.675

High

397701

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

4

0

High-throughput

0.670

High

283762

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

3

5

High-throughput

0.667

High

397676

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

3

1

High-throughput

0.667

High

397713

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

3

1

High-throughput

0.662

High

275230

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

1

High-throughput

0.628

High

397664

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

2

1

High-throughput

0.601

High

397697

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

1

High-throughput

0.601

High

397670

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

3

High-throughput

0.574

High

397702

YIPF3
Protein YIPF3

2

1

High-throughput

0.574

High

183808

NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

1

1

High-throughput

0.536

High

209731

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

1

High-throughput

0.536

High

328490

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

2

High-throughput

0.536

High

397668

NK1R
Substance-P receptor

1

1

High-throughput

0.536

High

397678

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

2

High-throughput

0.536

High

397685

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

1

High-throughput

0.536

High

397691

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

2

High-throughput

0.536

High

397692

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

397703

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.536

High

397704

RM18
Large ribosomal subunit protein uL18m

1

1

High-throughput

0.536

High

397710

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

1

High-throughput

0.536

High

397663

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.513

High

397694

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.513

High

397706

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.513

High

397712

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.513

High

397673

CTCF
Transcriptional repressor CTCF

1

1

Small-scale

0.508

High

397680

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.494

High

165885

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.489

High

230738

EXTL3
Exostosin-like 3

1

1

High-throughput

0.489

High

397665

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

1

1

High-throughput

0.489

High

397667

FPR2
N-formyl peptide receptor 2

1

2

High-throughput

0.489

High

397669

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

3

High-throughput

0.489

High

397671

CXA8
Gap junction alpha-8 protein

1

2

High-throughput

0.489

High

397672

AGRE5
Adhesion G protein-coupled receptor E5

1

2

High-throughput

0.489

High

397675

CCR6
C-C chemokine receptor type 6

1

1

High-throughput

0.489

High

397683

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

2

High-throughput

0.489

High

397696

CREL1
Protein disulfide isomerase CRELD1

1

3

High-throughput

0.489

High

397709

GPR35
G-protein coupled receptor 35

1

3

High-throughput

0.489

High

397674

DNLI4
DNA ligase 4

1

1

High-throughput

0.481

High

397698

IMP1L
Mitochondrial inner membrane protease subunit 1

1

2

High-throughput

0.479

High

397699

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.479

High

397705

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

1

High-throughput

0.479

High

397695

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

397679

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

2

Small-scale

0.445

High

397666

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.439

High

105089

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

159458

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.437

High

397660

SP1
Transcription factor Sp1

1

1

Small-scale

0.417

High

397681

RAC1
Ras-related C3 botulinum toxin substrate 1

2

0

High-throughput

0.298

High

397684

ATM
Serine-protein kinase ATM

1

0

High-throughput

0.282

High

397677

EMP3
Epithelial membrane protein 3

1

0

High-throughput

0.279

Low

397682

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.279

Low

397687

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.279

Low

397689

GOGA7
Golgin subfamily A member 7

1

0

High-throughput

0.279

Low

397693

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.279

Low

397707

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

397708

AT133
Polyamine-transporting ATPase 13A3

1

0

High-throughput

0.279

Low

397700

NKX31
Homeobox protein Nkx-3.1

1

0

Small-scale

0.251

Low

397686

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

397688

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

397690

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

0

High-throughput

0.249

Low

397661

ZNF16
Zinc finger protein 16

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025