HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34599178
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 263
+	Hs
		475358 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00
+	Hs
		156205 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	At
		189234 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA7B_ARATH (4-233): 4.98e-96: 283: 32.34
+	At
		188704 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA1B_ARATH (1-240): 1.35e-94: 280: 50.00
+	Hs
		475369 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81
+	At
		709289 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA1A_ARATH (1-238): 1.05e-93: 278: 50.00
+	Hs
		475547 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	At
		188696 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA2A_ARATH (1-237): 1.71e-93: 276: 32.64
+	Hs
		474931 UBB_HUMAN (3-157): 6.34e-67: 205: 32.26		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	At
		1091773 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA2B_ARATH (1-237): 1.1e-92: 274: 32.64
+	At
		286456 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA4A_ARATH (1-245): 1.92e-91: 272: 28.85
+	At
		286449 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA6A_ARATH (1-240): 4.34e-91: 270: 29.03
+	Hs
		171475 UBD_HUMAN (15-157): 1.31e-40: 135: 24.32		PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00
+	Hs
		156201 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	Hs
		397797 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81
+	Hs
		397877 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	Hs
		397788 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	Hs
		156170 UBD_HUMAN (15-157): 1.31e-40: 135: 24.32		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	Hs
		171478 UBD_HUMAN (15-157): 1.31e-40: 135: 24.32		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	At
		672527 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		PSA7A_ARATH (5-218): 8.98e-37: 132: 35.32