Protein: 5HT1B
5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B)

Gene: 5HT1B, HTR1B
Organism: Homo sapiens
Interactions: 62
UniProt ID: P28222

Gene Ontology (top 5):
GO:0001586 - Gi/o-coupled serotonin receptor activity
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701435

CD209
CD209 antigen

3

0

High-throughput

0.638

High

701427

MDFI
MyoD family inhibitor

3

1

High-throughput

0.630

High

701397

5HT1D
5-hydroxytryptamine receptor 1D

1

15

Small-scale

0.618

High

701399

ACTN2
Alpha-actinin-2

2

1

High-throughput

0.553

High

156983

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.553

High

230757

EXTL3
Exostosin-like 3

1

2

High-throughput

0.536

High

376724

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

High-throughput

0.536

High

443671

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

5

High-throughput

0.536

High

680235

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

5

High-throughput

0.536

High

701402

SATT
Neutral amino acid transporter A

1

1

High-throughput

0.536

High

701403

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

1

High-throughput

0.536

High

701406

KDSR
3-ketodihydrosphingosine reductase

1

5

High-throughput

0.536

High

701409

MSMO1
Methylsterol monooxygenase 1

1

2

High-throughput

0.536

High

701416

TM87A
Transmembrane protein 87A

1

2

High-throughput

0.536

High

701424

CERS2
Ceramide synthase 2

1

9

High-throughput

0.536

High

701430

ELOV1
Very long chain fatty acid elongase 1

1

1

High-throughput

0.536

High

701432

TTYH3
Protein tweety homolog 3

1

2

High-throughput

0.536

High

701436

GPC5C
G-protein coupled receptor family C group 5 member C

1

7

High-throughput

0.536

High

701437

LCAP
Leucyl-cystinyl aminopeptidase

1

3

High-throughput

0.536

High

701438

TMCC3
Transmembrane and coiled-coil domain protein 3

1

1

High-throughput

0.536

High

184122

RER1
Protein RER1

1

0

High-throughput

0.513

High

701413

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

0

High-throughput

0.513

High

701426

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

701428

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.513

High

701429

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.513

High

701434

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

701440

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

226404

SNG2
Synaptogyrin-2

1

3

High-throughput

0.489

High

397784

ATP8
ATP synthase F(0) complex subunit 8

1

1

High-throughput

0.489

High

665523

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

1

High-throughput

0.489

High

701400

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

1

High-throughput

0.489

High

701407

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

1

High-throughput

0.489

High

701410

GXLT1
Glucoside xylosyltransferase 1

1

1

High-throughput

0.489

High

701411

RETR3
Reticulophagy regulator 3

1

3

High-throughput

0.489

High

701415

XXLT1
Xyloside xylosyltransferase 1

1

1

High-throughput

0.489

High

701417

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

1

High-throughput

0.489

High

701418

GOGA5
Golgin subfamily A member 5

1

3

High-throughput

0.489

High

701420

SYNE2
Nesprin-2

1

4

High-throughput

0.489

High

701421

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

2

High-throughput

0.489

High

701422

FAM3C
Protein FAM3C

1

2

High-throughput

0.489

High

701423

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.489

High

701433

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

701441

SNX13
Sorting nexin-13

1

9

High-throughput

0.489

High

701401

SYUA
Alpha-synuclein

1

3

High-throughput

0.481

High

648093

NDKB
Nucleoside diphosphate kinase B

1

1

High-throughput

0.470

High

178908

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.279

Low

269992

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.279

Low

276947

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.279

Low

298673

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.279

Low

360253

COX1
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.279

Low

367172

ATP6
ATP synthase F(0) complex subunit a

1

0

High-throughput

0.279

Low

701398

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.279

Low

701404

ATP68
ATP synthase F(0) complex subunit j, mitochondrial

1

0

High-throughput

0.279

Low

701405

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

0

High-throughput

0.279

Low

701408

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.279

Low

701412

GLBL2
Beta-galactosidase-1-like protein 2

1

0

High-throughput

0.279

Low

701414

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

701419

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

701425

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.279

Low

701431

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

701442

RFNG
Beta-1,3-N-acetylglucosaminyltransferase radical fringe

1

0

High-throughput

0.279

Low

701439

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025