HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: MYO1E (Q12965)
Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E)
Gene: MYO1E

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33024031
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 1108
+	At
		98845 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		MYO17_ARATH (2-1070): 0: 1060: 27.25
+	Hs
		475417 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		MYH9_HUMAN (3-1087): 0: 1020: 26.87
+	Hs
		397813 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		MYH9_HUMAN (3-1087): 0: 1020: 26.87
+	Hs
		397814 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		MYH10_HUMAN (6-1087): 0: 1005: 26.78
+	Mm
		476930 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		MYH9_MOUSE (3-1087): 0: 1024: 26.78
+	Mm
		476828 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		MYH10_MOUSE (6-1087): 0: 1009: 26.69
+	Hs
		214468 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		MYO1B_HUMAN (20-720): 0: 621: 46.27
+	Hs
		297276 UBB_HUMAN (3-157): 6.34e-67: 205: 32.26		MYO1D_HUMAN (20-719): 0: 569: 42.54
+	Rn
		1144144 UBC_RAT (2-110): 2.29e-33: 125: 28.44		MYO1D_RAT (20-719): 0: 569: 42.54
+	Hs
		117555 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		MYO1C_HUMAN (698-843): 2e-10: 67.4: 31.76
+	Hs
		398149 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		MYO5A_HUMAN (689-1083): 5.07e-09: 62.8: 7.24
+	Mm
		476960 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		MYO5A_MOUSE (690-1083): 2.22e-12: 74: 10.31