HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33024031, 16009940
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 4684
+	Hs
		475789 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		PLEC_HUMAN (1-4684): 0: 1783: 100.00
+	Mm
		477041 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		PLEC_MOUSE (1-4684): 0: 1747: 93.29
+	Hs
		397748 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94
+	Rn
		1144315 UBC_RAT (2-110): 2.29e-33: 125: 28.44		ACTN1_RAT (153-876): 3.38e-112: 383: 24.07
+	Mm
		476860 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		ACTN1_MOUSE (153-876): 2.62e-111: 381: 24.20
+	Hs
		475541 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75
+	Hs
		397873 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75
+	Hs
		476576 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		MACF1_HUMAN (3704-4616): 3.72e-10: 69.3: 14.92
+	Hs
		924278 RL40_HUMAN (3-82): 1.77e-34: 119: 27.50		SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53
+	Rn
		1144216 UBC_RAT (2-110): 2.29e-33: 125: 28.44		Q6XD99_RAT (1531-3190): 1.96e-15: 86.6: 9.24
+	Mm
		476949 UBC_MOUSE (2-110): 1.68e-33: 126: 28.44		DYST_MOUSE (4325-4624): 7.75e-09: 65: 17.00