Protein: ECP
Eosinophil cationic protein (ECP) (EC 3.1.27.-) (Ribonuclease 3) (RNase 3)

Gene: ECP, RNASE3
Organism: Homo sapiens
Interactions: 22
UniProt ID: P12724

Gene Ontology (top 5):
GO:0001530 - lipopolysaccharide binding
GO:0002227 - innate immune response in mucosa
GO:0003676 - nucleic acid binding
GO:0004519 - endonuclease activity
GO:0004540 - RNA nuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

555201

RINI
Ribonuclease inhibitor

2

5

High-throughput

0.726

High

506920

POTEI
POTE ankyrin domain family member I

2

3

High-throughput

0.628

High

555205

ACTB
Actin, cytoplasmic 1

2

4

High-throughput

0.628

High

555206

ACTA
Actin, aortic smooth muscle

2

3

High-throughput

0.628

High

555209

ACTBL
Beta-actin-like protein 2

2

3

High-throughput

0.628

High

555214

GTPB2
GTP-binding protein 2

2

2

High-throughput

0.628

High

555210

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.489

High

261929

RNH1
Ribonuclease H1

1

1

High-throughput

0.445

High

555203

FBLN1
Fibulin-1

1

3

High-throughput

0.445

High

555207

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.445

High

555208

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

3

High-throughput

0.445

High

555215

CRIM1
Cysteine-rich motor neuron 1 protein

1

1

High-throughput

0.445

High

281869

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.407

High

376468

LDLR
Low-density lipoprotein receptor

1

1

High-throughput

0.407

High

555211

RCN3
Reticulocalbin-3

1

1

High-throughput

0.407

High

555212

PCD16
Protocadherin-16

1

1

High-throughput

0.407

High

343668

GGPPS
Geranylgeranyl pyrophosphate synthase

3

0

High-throughput

0.345

High

555213

UBAC1
Ubiquitin-associated domain-containing protein 1

3

0

High-throughput

0.345

High

555204

BLK
Tyrosine-protein kinase Blk

2

0

High-throughput

0.328

High

555216

EFR3B
Protein EFR3 homolog B

2

0

High-throughput

0.328

High

555202

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

0

High-throughput

0.279

Low

238369

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025