HitPredict

Interactor 1: HP1 (P05205)
Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen)
Gene: Su(var)205

Interactor 2: EZ (P42124)
Histone-lysine N-methyltransferase E(z) (EC 2.1.1.356) (Lysine N-methyltransferase 6) (Protein enhancer of zeste)
Gene: E(z)

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 25954320, 12408863
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0031507 - heterochromatin formation
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 206
Dm

1 760
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024