Interactor 1: EDN1 (P05305)
Endothelin-1 (Preproendothelin-1) (PPET1) [Cleaved into: Endothelin-1 (ET-1); Big endothelin-1]
Gene: EDN1

Interactor 2: EDN1 (P05305)
Endothelin-1 (Preproendothelin-1) (PPET1) [Cleaved into: Endothelin-1 (ET-1); Big endothelin-1]
Gene: EDN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.90 0.674

The method score is based on:

Property Details
Experiments 15568807
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Endothelin~Endothelin
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001516 - prostaglandin biosynthetic process
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001701 - in utero embryonic development
GO:0001821 - histamine secretion
and 130 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024