HitPredict

Interactor 1: ICAM1 (P05362)
Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)
Gene: ICAM1

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 28514442, 23463506
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 532 Hs			1 448
+	Hs
		400083 ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		399950 ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Rn
		530221 NCAM1_RAT (9-524): 9.1e-85: 282: 13.64		TBA1A_RAT (1-439): 0: 712: 97.04
+	Hs
		427993 NCAM1_HUMAN (9-524): 1.88e-83: 278: 13.01		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		530251 ICAM2_HUMAN (13-227): 2.73e-70: 228: 33.04		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		581662 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		933663 ICAM5_HUMAN (1-206): 1.39e-17: 88.4: 16.29		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		581661 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		428008 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		581663 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBB4B_HUMAN (1-437): 0: 695: 40.28