HitPredict

Interactor 1: ICAM1 (P05362)
Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)
Gene: ICAM1

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 532 Hs			1 450
+	Hs
		400075 ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		399950 ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		400112 ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		381098 ICAM1_HUMAN (1-532): 7.16e-102: 318: 100.00		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		427993 NCAM1_HUMAN (9-524): 1.88e-83: 278: 13.01		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Rn
		530222 NCAM1_RAT (9-524): 9.1e-85: 282: 13.64		TBB2A_RAT (1-430): 0: 700: 93.49
+	Hs
		530247 ICAM2_HUMAN (13-227): 2.73e-70: 228: 33.04		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		1037462 ROBO1_HUMAN (21-525): 1.61e-32: 135: 10.51		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		381339 ROBO1_HUMAN (21-525): 1.61e-32: 135: 10.51		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		581762 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		428008 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		581663 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		581847 VCAM1_HUMAN (228-500): 5e-20: 95.8: 18.57		TBB6_HUMAN (1-446): 0: 700: 92.38