HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RAB43 (Q86YS6)
Ras-related protein Rab-43 (Ras-related protein Rab-41)
Gene: RAB43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, Pkinase~Ras, RBD~Ras
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 212
+	Hs
		400608 RAF1_HUMAN (1-648): 0: 637: 100.00		RAB1A_HUMAN (8-212): 4.7e-88: 259: 42.72
+	Hs
		401463 RAF1_HUMAN (1-648): 0: 637: 100.00		RAB1B_HUMAN (11-212): 9.04e-88: 259: 44.55
+	Hs
		62179 RAF1_HUMAN (1-648): 0: 637: 100.00		RAB19_HUMAN (12-204): 1.21e-81: 243: 56.48
+	Hs
		400604 RAF1_HUMAN (1-648): 0: 637: 100.00		RB11A_HUMAN (8-211): 4.4e-80: 239: 41.86
+	Hs
		400574 RAF1_HUMAN (1-648): 0: 637: 100.00		RAB8A_HUMAN (11-212): 6.44e-80: 238: 42.44
+	Hs
		578441 BRAF_HUMAN (39-647): 9.6e-166: 494: 56.02		RAB1A_HUMAN (8-212): 4.7e-88: 259: 42.72
+	Hs
		521281 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		RB11A_HUMAN (8-211): 4.4e-80: 239: 41.86
+	Hs
		557324 SRC_HUMAN (331-607): 2.21e-106: 334: 33.45		RB11B_HUMAN (8-211): 4.55e-80: 240: 40.55
+	Hs
		557200 SRC_HUMAN (331-607): 2.21e-106: 334: 33.45		RB11A_HUMAN (8-211): 4.4e-80: 239: 41.86
+	Hs
		463048 YES_HUMAN (329-607): 9.75e-106: 332: 33.92		RB11A_HUMAN (8-211): 4.4e-80: 239: 41.86