HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	14550555, 24999758, 25609649
Identification Methods	pull down, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 656
+	Hs
		318557 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		401527 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		967119 CREB5_HUMAN (209-329): 7.99e-23: 100: 26.40		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		569612 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		212104 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		HTSF1_HUMAN (310-448): 3.35e-28: 122: 20.55