HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.758

Property	Details
Experiments	25609649, 12615916, 36251994, 28514442, 27534417, 14739464, 31155351, 33961781, 37689310, 15994960, 25117710
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 331 Hs			1 731
+	Hs
		566776 JUNB_HUMAN (1-331): 3.94e-63: 205: 43.89		COP1_HUMAN (1-731): 0: 540: 100.00
+	Hs
		568100 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		COP1_HUMAN (1-731): 0: 540: 100.00
+	Hs
		569888 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		COP1_HUMAN (1-731): 0: 540: 100.00
+	Hs
		402320 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		196941 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PRP4_HUMAN (511-730): 7.51e-41: 159: 16.59
+	Hs
		402538 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33
+	Hs
		401900 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49
+	Hs
		401754 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Mm
		1257400 CR3L1_MOUSE (121-303): 3.68e-23: 101: 17.94		FBXW7_MOUSE (452-730): 4.71e-69: 242: 17.15
+	Hs
		1281297 CR3L1_HUMAN (121-303): 5.84e-22: 98.2: 17.94		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		402083 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34
+	Hs
		402335 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67
+	Hs
		196953 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PRP4_HUMAN (511-730): 7.51e-41: 159: 16.59
+	Hs
		556850 CREB1_HUMAN (54-307): 2.89e-29: 116: 14.84		RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49
+	Hs
		556832 CREB1_HUMAN (54-307): 2.89e-29: 116: 14.84		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		267763 CEBPE_HUMAN (112-314): 1.46e-26: 107: 17.35		TAF5L_HUMAN (486-667): 2.48e-11: 68.9: 29.57
+	Hs
		569650 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49
+	Hs
		569504 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		569785 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34
+	Hs
		569952 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67