HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36629882, 25609649
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 299
+	Hs
		401513 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		547843 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		547731 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		569999 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Hs
		569287 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Hs
		569224 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		STOM_HUMAN (1-286): 2.42e-84: 256: 17.93