Interactor 1: ERF3 (P05453)
Eukaryotic peptide chain release factor GTP-binding subunit (EC 3.6.5.-) (ERF-3) (ERF3) (ERF2) (G1 to S phase transition protein 1) (Omnipotent suppressor protein 2) (PSI no more protein 2) (Polypeptide release factor 3) (Translation release factor 3)
Gene: SUP35

Interactor 2: ERF3 (P05453)
Eukaryotic peptide chain release factor GTP-binding subunit (EC 3.6.5.-) (ERF-3) (ERF3) (ERF2) (G1 to S phase transition protein 1) (Omnipotent suppressor protein 2) (PSI no more protein 2) (Polypeptide release factor 3) (Translation release factor 3)
Gene: SUP35

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.995

The method score is based on:

Property Details
Experiments 17295405, 21113168, 21219467, 24123863, 15383837, 16642217, 25568955, 17975557, 29078994, 31803017, 18324784, 18366654, 32101755, 18353968, 18400756, 18780782, 18757753, 18833196, 19345193, 35194850 and 17 others

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Identification Methods pull down, x-ray crystallography, biochemical, protein complementation assay, affinity chromatography technology, nuclear magnetic resonance, atomic force microscopy, classical fluorescence spectroscopy, comigration in sds page, cosedimentation in solution and 2 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU_D3, GTP_EFTU_D2~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D3, GTP_EFTU_D3~GTP_EFTU_D3
Common GO terms GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0003729 - mRNA binding
GO:0003747 - translation release factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
and 6 others

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Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 685
Sc

1 685
+ Hs
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Sc
+ Zm
+ Zm
+ Zm
+ Zm

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Last updated: 15 Jul 2024