HitPredict

Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: KPCE (P16054)
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
Gene: Prkce

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 11834516, 11139474
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase, C1_1~SH2, C2~SH2
Common GO terms GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 11 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 535
Mm

1 737
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024