HitPredict

Interactor 1: KIT (P05532)
Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
Gene: KIT

Interactor 2: P85A (P26450)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: Pik3r1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 1370584, 10679268, 22378847, 12878163, 10022833
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0005911 - cell-cell junction
GO:0010628 - positive regulation of gene expression
GO:0030183 - B cell differentiation
GO:0030335 - positive regulation of cell migration
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 979
Mm

1 724
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024