HitPredict

Interactor 1: AP2A (P05549)
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
Gene: TFAP2A

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24999758, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 656
+	Hs
		358445 AP2A_HUMAN (1-437): 0: 685: 100.00		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		118527 AP2A_HUMAN (1-437): 0: 685: 100.00		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16
+	Hs
		403574 AP2A_HUMAN (1-437): 0: 685: 100.00		CO1A2_HUMAN (4-301): 3.82e-16: 84.9: 12.95
+	Hs
		358546 AP2C_HUMAN (1-437): 0: 557: 62.66		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		118590 AP2C_HUMAN (1-437): 0: 557: 62.66		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16
+	Hs
		436041 AP2C_HUMAN (1-437): 0: 557: 62.66		CO1A2_HUMAN (4-301): 3.82e-16: 84.9: 12.95
+	Hs
		358639 AP2C_HUMAN (1-437): 0: 557: 62.66		CO3A1_HUMAN (21-534): 1.77e-13: 76.4: 12.60