HitPredict

Interactor 1: CTC1 (Q2NKJ3)
CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B)
Gene: CTC1

Interactor 2: STN1 (Q9H668)
CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog)
Gene: STN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.934

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781, 22763445, 19854130
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CTC1~STN1_2, CTC1~tRNA_anti-codon
Common GO terms	GO:0000723 - telomere maintenance GO:0000781 - chromosome, telomeric region GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 6 others more... GO:0010833 - telomere maintenance via telomere lengthening GO:0016233 - telomere capping GO:0032211 - negative regulation of telomere maintenance via telomerase GO:0042162 - telomeric DNA binding GO:0045740 - positive regulation of DNA replication GO:1990879 - CST complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	1217
Hs

1	368

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024