HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 34349018
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008542 - visual learning
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 798 Hs			1 3969
+	Hs
		403892 ITB1_HUMAN (1-798): 0: 794: 100.00		EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54
+	Dm
		422800 NOTCH_DROME (345-570): 1.3e-09: 64.4: 12.85		LUBEL_DROME (185-1127): 1.73e-16: 89.7: 11.69