Protein: NCLN
BOS complex subunit NCLN (Nicalin) (Nicastrin-like protein)

Gene: NCLN
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q969V3

Gene Ontology (top 5):
GO:0003140 - determination of left/right asymmetry in lateral mesoderm
GO:0005789 - endoplasmic reticulum membrane
GO:0009966 - regulation of signal transduction
GO:0016020 - membrane
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1069037

NOMO1
BOS complex subunit NOMO1

5

3

Small-scale

0.714

High

946054

DLK1
Protein delta homolog 1

3

0

High-throughput

0.638

High

1282485

FBX6
F-box only protein 6

4

1

High-throughput

0.633

High

1126887

NOMO2
BOS complex subunit NOMO2

2

3

High-throughput

0.628

High

1204806

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.618

High

1240708

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.618

High

626570

FPR2
N-formyl peptide receptor 2

2

0

High-throughput

0.602

High

1282461

CCD47
PAT complex subunit CCDC47

2

0

Small-scale

0.585

High

1282495

VAPA
Vesicle-associated membrane protein-associated protein A

2

0

High-throughput

0.585

High

1282500

TMCO1
Calcium load-activated calcium channel

2

0

Small-scale

0.585

High

228284

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

913036

ARF6
ADP-ribosylation factor 6

2

0

High-throughput

0.559

High

1282466

CALR3
Calreticulin-3

2

0

High-throughput

0.559

High

123679

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.536

High

170911

PGRC2
Membrane-associated progesterone receptor component 2

1

1

High-throughput

0.536

High

172161

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

505449

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.536

High

561650

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.536

High

931549

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

1

High-throughput

0.536

High

935955

NOMO3
BOS complex subunit NOMO3

1

3

High-throughput

0.536

High

1058788

LBR
Delta(14)-sterol reductase LBR

1

1

High-throughput

0.536

High

1282476

SC11C
Signal peptidase complex catalytic subunit SEC11C

1

1

High-throughput

0.536

High

1282496

DHCR7
7-dehydrocholesterol reductase

1

1

High-throughput

0.536

High

915887

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.533

High

1130416

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.528

High

118981

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.513

High

126839

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

152447

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.513

High

298700

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

390433

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.513

High

391078

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.513

High

513753

CP19A
Aromatase

1

0

High-throughput

0.513

High

736636

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

821603

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.513

High

883850

TMM33
Transmembrane protein 33

1

0

High-throughput

0.513

High

894886

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.513

High

913402

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.513

High

951684

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1050338

MLEC
Malectin

1

0

High-throughput

0.513

High

1053796

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1062468

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.513

High

1062609

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1126660

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.513

High

1156566

TM214
Transmembrane protein 214

1

0

High-throughput

0.513

High

1192158

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.513

High

1233912

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.513

High

1236942

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.513

High

1253647

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.513

High

1255491

LRC8C
Volume-regulated anion channel subunit LRRC8C

1

0

High-throughput

0.513

High

1262345

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.513

High

1281719

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.513

High

1282464

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.513

High

1282465

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.513

High

1282470

DERL1
Derlin-1

1

0

High-throughput

0.513

High

1282472

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.513

High

1282473

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.513

High

1282474

TM147
BOS complex subunit TMEM147

1

0

High-throughput

0.513

High

1282478

MAGT1
Magnesium transporter protein 1

1

0

High-throughput

0.513

High

1282484

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.513

High

1282498

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.513

High

1282501

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

1282504

TMX2
Thioredoxin-related transmembrane protein 2

1

0

High-throughput

0.513

High

1282505

TBL2
Transducin beta-like protein 2

1

0

High-throughput

0.513

High

1282506

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

1282508

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.513

High

281801

WFS1
Wolframin

1

0

High-throughput

0.493

High

791838

HD
Huntingtin

1

0

High-throughput

0.493

High

876173

PAR2
Proteinase-activated receptor 2

1

1

High-throughput

0.489

High

1067567

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.489

High

1282460

T106A
Transmembrane protein 106A

1

1

High-throughput

0.489

High

1282499

FBX2
F-box only protein 2

1

1

High-throughput

0.489

High

1282502

GPR55
G-protein coupled receptor 55

1

3

High-throughput

0.489

High

377567

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

393305

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.479

High

436443

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

545546

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.479

High

892527

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

894289

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.479

High

900774

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

925500

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

951212

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.479

High

1101945

TECT1
Tectonic-1

1

1

High-throughput

0.479

High

1282475

TACAN
Ion channel TACAN

1

1

High-throughput

0.479

High

133599

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

216292

CALU
Calumenin

1

0

High-throughput

0.458

High

322969

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

338805

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

385306

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

507170

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

525581

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

719044

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

726340

BASI
Basigin

1

0

High-throughput

0.458

High

750393

COIL
Coilin

1

0

High-throughput

0.458

High

881664

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

890323

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

917706

H4
Histone H4

1

0

High-throughput

0.458

High

998959

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1035955

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1042225

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1087965

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.458

High

1163779

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1165824

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1168619

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1255644

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

1268852

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1281293

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1282462

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1282463

PLD4
5'-3' exonuclease PLD4

1

0

High-throughput

0.458

High

1282471

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

1282486

SERC1
Serine incorporator 1

1

0

High-throughput

0.458

High

1282487

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

0

High-throughput

0.458

High

49352

T120B
Transmembrane protein 120B

1

1

High-throughput

0.437

High

120573

RHOD
Rho-related GTP-binding protein RhoD

1

11

High-throughput

0.437

High

297662

RHBT1
Rho-related BTB domain-containing protein 1

1

8

High-throughput

0.437

High

564640

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.437

High

852581

RND2
Rho-related GTP-binding protein RhoN

1

11

High-throughput

0.437

High

901216

RND3
Rho-related GTP-binding protein RhoE

1

13

High-throughput

0.437

High

1073462

KS6A1
Ribosomal protein S6 kinase alpha-1

1

1

High-throughput

0.437

High

1076698

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.437

High

1156661

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1183495

RHOU
Rho-related GTP-binding protein RhoU

1

10

High-throughput

0.437

High

1269200

RND1
Rho-related GTP-binding protein Rho6

1

12

High-throughput

0.437

High

1269304

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1282467

RHOV
Rho-related GTP-binding protein RhoV

1

9

High-throughput

0.437

High

1282477

RHBT2
Rho-related BTB domain-containing protein 2

1

8

High-throughput

0.437

High

1282481

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.437

High

1282483

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.437

High

1282489

T106B
Transmembrane protein 106B

1

1

High-throughput

0.437

High

1282492

ARL15
ADP-ribosylation factor-like protein 15

1

1

High-throughput

0.437

High

529522

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1241563

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

1282494

HACD3
Very-long-chain

1

0

High-throughput

0.426

High

642129

KRA59
Keratin-associated protein 5-9

1

0

High-throughput

0.299

High

374651

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.298

High

207084

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.279

Low

320134

RAB3D
Ras-related protein Rab-3D

1

0

High-throughput

0.279

Low

519249

KCRB
Creatine kinase B-type

1

0

High-throughput

0.279

Low

1021032

BFSP1
Filensin

1

0

High-throughput

0.279

Low

1282468

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.279

Low

1282488

CBLN4
Cerebellin-4

1

0

High-throughput

0.279

Low

1282491

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.279

Low

127839

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.249

Low

132558

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

155420

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

205798

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

352676

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

429924

CATL1
Procathepsin L

1

0

High-throughput

0.249

Low

531934

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.249

Low

553368

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

578059

RL17
Large ribosomal subunit protein uL22

1

0

Small-scale

0.249

Low

651883

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721096

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

779864

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

824256

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

832627

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

908924

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

941270

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1080209

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1086700

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1101205

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1148715

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1171121

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1188674

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1220955

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1243880

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1272514

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

1273166

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.249

Low

1281809

FBX32
F-box only protein 32

1

0

High-throughput

0.249

Low

1282469

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.249

Low

1282479

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

1282480

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.249

Low

1282482

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1282490

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.249

Low

1282493

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low

1282497

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1282503

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1282507

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.249

Low

1097

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024