HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010008 - endosome membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 798 Hs			1 236
+	Hs
		403911 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		403858 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		403851 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		403841 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		403770 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		403762 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		403845 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		403842 ITB1_HUMAN (1-798): 0: 794: 100.00		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		403967 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		574521 ITB5_HUMAN (19-792): 0: 660: 42.64		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		545199 ITB5_HUMAN (19-792): 0: 660: 42.64		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		574577 ITB5_HUMAN (19-792): 0: 660: 42.64		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		639928 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		639924 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		639922 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		892650 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		545674 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		901003 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		894539 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		545337 NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43