HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	30833792, 32409323, 22268729
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 798 Hs			1 293
+	Hs
		574580 ITB5_HUMAN (19-792): 0: 660: 42.64		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		403996 ITB1_HUMAN (1-798): 0: 794: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		574583 ITB5_HUMAN (19-792): 0: 660: 42.64		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		624336 TENA_HUMAN (336-474): 5.37e-16: 85.2: 9.79		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1154503 TEN4_HUMAN (356-480): 1.24e-09: 64.4: 9.22		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1350098 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1256715 SNED1_HUMAN (510-744): 5.08e-22: 104: 14.29		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		980571 NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		804367 NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17