HitPredict

Interactor 1: JUN (P05627)
Transcription factor Jun (AH119) (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A)
Gene: JUN

Interactor 2: CCL4 (P14097)
C-C motif chemokine 4 (Immune activation protein 2) (ACT-2) (ACT2) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4)
Gene: CCL4

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19299558
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 334 Mm			1 92
+	Mm
		404109 JUN_MOUSE (1-334): 1.42e-101: 303: 100.00		CCL2_MOUSE (1-92): 1.22e-34: 117: 38.71
+	Hs
		402085 JUN_HUMAN (1-334): 5.59e-99: 296: 94.61		CCL14_HUMAN (1-92): 1.14e-35: 118: 45.16
+	Mm
		404144 JUN_MOUSE (1-334): 1.42e-101: 303: 100.00		CCL12_MOUSE (1-90): 1.62e-31: 107: 30.77
+	Mm
		404135 JUN_MOUSE (1-334): 1.42e-101: 303: 100.00		CCL7_MOUSE (1-91): 5.03e-23: 86.2: 31.52
+	Mm
		500592 ATF7_MOUSE (49-332): 1.7e-48: 169: 19.80		CCL3_MOUSE (1-92): 1.06e-36: 120: 59.78
+	Hs
		526555 CREB1_HUMAN (36-310): 2.27e-35: 132: 16.56		CCL4_HUMAN (1-92): 1.69e-37: 122: 76.09
+	Hs
		528231 ATF2_HUMAN (44-334): 1.1e-40: 150: 19.02		CCL5_HUMAN (1-92): 5.87e-28: 98.5: 46.74
+	Hs
		486222 CREB1_HUMAN (36-310): 2.27e-35: 132: 16.56		CCL3_HUMAN (1-92): 6.17e-35: 116: 58.70
+	Hs
		1246073 CR3L1_HUMAN (88-308): 5.13e-31: 124: 16.74		CC4L_HUMAN (1-92): 2.11e-33: 112: 76.09
+	Hs
		528232 CREB1_HUMAN (36-310): 2.27e-35: 132: 16.56		CCL5_HUMAN (1-92): 5.87e-28: 98.5: 46.74