HitPredict

Interactor 1: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Interactor 2: TCHP (Q9BT92)
Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)
Gene: TCHP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	15731013, 34079125
Identification Methods	two hybrid, pull down, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045095 - keratin filament
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 498
+	Hs
		444536 K2C7_HUMAN (1-464): 4.13e-154: 448: 60.34		GOGA4_HUMAN (15-475): 8.86e-09: 60.5: 11.45
+	Hs
		318873 K2C75_HUMAN (2-405): 3.9e-79: 258: 64.04		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		531622 K2C5_HUMAN (56-405): 9.54e-66: 223: 71.02		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		359528 K2C6A_HUMAN (56-405): 8.09e-65: 220: 70.74		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1270301 KRT35_HUMAN (5-402): 8.85e-64: 215: 25.31		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1055193 K1H2_HUMAN (88-402): 1.27e-62: 212: 27.22		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00