HitPredict

Interactor 1: HEPS (P05981)
Serine protease hepsin (EC 3.4.21.106) (Transmembrane protease serine 1) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]
Gene: HPN

Interactor 2: TOR2A (Q5JU69)
Torsin-2A (Torsin family 2 member A) (Torsin-related protein 1)
Gene: TOR2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 321
+	Hs
		151960 HEPS_HUMAN (1-417): 4.99e-176: 499: 100.00		TOR1A_HUMAN (6-320): 1.47e-124: 361: 41.59
+	Hs
		409559 HEPS_HUMAN (1-417): 4.99e-176: 499: 100.00		TOR3A_HUMAN (10-321): 1.28e-108: 323: 36.59
+	Hs
		152037 TMPSD_HUMAN (29-411): 1.81e-125: 376: 34.46		TOR1A_HUMAN (6-320): 1.47e-124: 361: 41.59
+	Hs
		409536 HEPS_HUMAN (1-417): 4.99e-176: 499: 100.00		TOR2X_HUMAN (1-197): 4.44e-71: 222: 100.00
+	Hs
		884426 TMPS3_HUMAN (27-406): 1.31e-132: 390: 35.94		TOR3A_HUMAN (10-321): 1.28e-108: 323: 36.59
+	Hs
		1316654 TMPSD_HUMAN (29-411): 1.81e-125: 376: 34.46		TOR3A_HUMAN (10-321): 1.28e-108: 323: 36.59
+	Hs
		1330327 TMPS5_HUMAN (11-403): 2.43e-126: 374: 33.08		TOR3A_HUMAN (10-321): 1.28e-108: 323: 36.59
+	Hs
		371472 KLKB1_HUMAN (90-416): 1.17e-95: 301: 31.85		TOR3A_HUMAN (10-321): 1.28e-108: 323: 36.59
+	Hs
		737505 TMPS4_HUMAN (13-406): 8e-131: 385: 32.58		LONM_HUMAN (1-320): 2.42e-68: 231: 13.53
+	Hs
		177831 TMPS2_HUMAN (13-406): 5.55e-120: 359: 30.73		LONM_HUMAN (1-320): 2.42e-68: 231: 13.53
+	Hs
		152058 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR1A_HUMAN (6-320): 1.47e-124: 361: 41.59
+	Hs
		737393 TM11B_HUMAN (153-403): 4.12e-101: 308: 40.00		LONM_HUMAN (1-320): 2.42e-68: 231: 13.53
+	Hs
		1128311 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR2A_HUMAN (1-321): 6.15e-120: 349: 100.00
+	Hs
		1330730 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR3A_HUMAN (10-321): 1.28e-108: 323: 36.59
+	Hs
		1231544 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR2X_HUMAN (1-197): 4.44e-71: 222: 100.00