Protein: SE1L1
Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)

Gene: SE1L1, SEL1L
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q9UBV2

Gene Ontology (top 5):
GO:0000836 - Hrd1p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006641 - triglyceride metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1198703

SYVN1
E3 ubiquitin-protein ligase synoviolin

18

6

Small-scale

0.763

High

1034556

OS9
Protein OS-9

15

3

Small-scale

0.762

High

1326107

DERL2
Derlin-2

5

3

Small-scale

0.709

High

1268026

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

5

4

Small-scale

0.702

High

1288839

ERLEC
Endoplasmic reticulum lectin 1

4

4

Small-scale

0.683

High

1354371

UB2J1
Ubiquitin-conjugating enzyme E2 J1

3

7

Small-scale

0.675

High

1218637

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

4

0

Small-scale

0.674

High

1354377

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

4

0

Small-scale

0.661

High

1287213

FAF2
FAS-associated factor 2

2

2

Small-scale

0.628

High

644728

NKG2D
NKG2-D type II integral membrane protein

1

9

High-throughput

0.618

High

991266

NKG2E
NKG2-E type II integral membrane protein

1

9

High-throughput

0.618

High

1265964

CLC2B
C-type lectin domain family 2 member B

1

9

High-throughput

0.618

High

339082

EGFR
Epidermal growth factor receptor

2

7

High-throughput

0.611

High

1354326

FA8A1
Protein FAM8A1

2

0

Small-scale

0.608

High

1328624

UN93B
Protein unc-93 homolog B1

2

0

High-throughput

0.595

High

265564

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

2

2

Small-scale

0.594

High

1296661

CALR3
Calreticulin-3

2

3

High-throughput

0.584

High

1313093

DERL1
Derlin-1

2

3

Small-scale

0.584

High

1318318

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

2

4

Small-scale

0.584

High

1344590

FBX6
F-box only protein 6

2

5

High-throughput

0.584

High

589999

TRYB2
Tryptase beta-2

2

4

High-throughput

0.574

High

1203296

AMGO3
Amphoterin-induced protein 3

2

4

High-throughput

0.574

High

1264035

CBPA5
Carboxypeptidase A5

2

2

High-throughput

0.574

High

1344434

CHSTC
Carbohydrate sulfotransferase 12

2

1

High-throughput

0.574

High

1354368

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

2

High-throughput

0.574

High

1354375

HYOU1
Hypoxia up-regulated protein 1

1

6

Small-scale

0.561

High

1348295

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

2

2

High-throughput

0.558

High

538436

ENPL
Endoplasmin

1

9

High-throughput

0.536

High

1345786

CBLN4
Cerebellin-4

1

12

High-throughput

0.536

High

1087994

PTPRO
Receptor-type tyrosine-protein phosphatase O

2

2

High-throughput

0.533

High

370628

ESR1
Estrogen receptor

2

9

High-throughput

0.521

High

714701

CNR2
Cannabinoid receptor 2

1

0

Small-scale

0.513

High

824979

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.513

High

1062931

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

Small-scale

0.513

High

146418

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

3

High-throughput

0.489

High

236340

B4GT3
Beta-1,4-galactosyltransferase 3

1

1

High-throughput

0.489

High

354784

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

2

High-throughput

0.489

High

362493

C1QA
Complement C1q subcomponent subunit A

1

14

High-throughput

0.489

High

448959

CD48
CD48 antigen

1

2

High-throughput

0.489

High

596143

C4BPB
C4b-binding protein beta chain

1

2

High-throughput

0.489

High

606944

IDS
Iduronate 2-sulfatase

1

2

High-throughput

0.489

High

726550

TIMP3
Metalloproteinase inhibitor 3

1

8

High-throughput

0.489

High

1030772

SLAF1
Signaling lymphocytic activation molecule

1

3

High-throughput

0.489

High

1067641

P2RY6
P2Y purinoceptor 6

1

3

High-throughput

0.489

High

1081637

NTRK3
NT-3 growth factor receptor

1

16

High-throughput

0.489

High

1190791

LYZL2
Lysozyme-like protein 2

1

3

High-throughput

0.489

High

1199107

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.489

High

1219083

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1262452

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.489

High

1292449

PLPR2
Phospholipid phosphatase-related protein type 2

1

1

High-throughput

0.489

High

1326683

NYX
Nyctalopin

1

1

High-throughput

0.489

High

1329183

CHST8
Carbohydrate sulfotransferase 8

1

1

High-throughput

0.489

High

1332723

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.489

High

1354370

KLK5
Kallikrein-5

1

7

High-throughput

0.489

High

168067

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

216351

CALU
Calumenin

1

1

High-throughput

0.479

High

301451

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

4

Small-scale

0.479

High

387661

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

390599

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

Small-scale

0.479

High

443108

ITA5
Integrin alpha-5

1

7

Small-scale

0.479

High

502643

BIP
Endoplasmic reticulum chaperone BiP

1

10

Small-scale

0.479

High

532012

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.479

High

726456

BASI
Basigin

1

4

Small-scale

0.479

High

875397

TERA
Transitional endoplasmic reticulum ATPase

1

4

Small-scale

0.479

High

890491

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

1074306

SHH
Sonic hedgehog protein

1

1

Small-scale

0.479

High

1240822

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

1267623

UBXN4
UBX domain-containing protein 4

1

1

Small-scale

0.479

High

1284139

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

1313612

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

4

Small-scale

0.479

High

1349633

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

1354206

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

1

Small-scale

0.479

High

1354367

AMFR
E3 ubiquitin-protein ligase AMFR

1

4

Small-scale

0.479

High

1354374

LOXL2
Lysyl oxidase homolog 2

1

7

High-throughput

0.479

High

1354376

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

1

Small-scale

0.479

High

431293

CATB
Cathepsin B

1

2

High-throughput

0.470

High

48030

TM129
E3 ubiquitin-protein ligase TM129

1

0

Small-scale

0.458

High

267262

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

0

Small-scale

0.458

High

1166033

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1286065

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

Small-scale

0.458

High

411516

INSR
Insulin receptor

1

12

High-throughput

0.457

High

435791

IGF1R
Insulin-like growth factor 1 receptor

1

13

High-throughput

0.457

High

529851

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

1241660

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.445

High

973275

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.439

High

206118

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

309129

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

385660

NTRK1
High affinity nerve growth factor receptor

1

16

High-throughput

0.437

High

403992

ITB1
Integrin beta-1

1

12

Small-scale

0.437

High

409264

K2C8
Keratin, type II cytoskeletal 8

1

3

Small-scale

0.437

High

434303

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

11

High-throughput

0.437

High

532358

PPA5
Tartrate-resistant acid phosphatase type 5

1

1

High-throughput

0.437

High

556489

ITB4
Integrin beta-4

1

12

Small-scale

0.437

High

584492

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

1

High-throughput

0.437

High

617071

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

3

High-throughput

0.437

High

941543

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

957530

VLDLR
Very low-density lipoprotein receptor

1

2

Small-scale

0.437

High

1066822

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1128937

EPHAA
Ephrin type-A receptor 10

1

6

High-throughput

0.437

High

1148844

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

1161015

SG11A
Sperm-associated antigen 11A

1

1

High-throughput

0.437

High

1168729

SYNE3
Nesprin-3

1

3

High-throughput

0.437

High

1172114

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1204857

GOLI
E3 ubiquitin-protein ligase RNF130

1

6

High-throughput

0.437

High

1269836

ESR2
Estrogen receptor beta

1

9

High-throughput

0.437

High

1292274

AURKB
Aurora kinase B

1

2

High-throughput

0.437

High

1346079

T106B
Transmembrane protein 106B

1

1

High-throughput

0.437

High

1348880

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.437

High

1354366

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.437

High

1354372

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

1354373

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

Small-scale

0.437

High

497729

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.407

High

996170

SG11B
Sperm-associated antigen 11B

1

1

High-throughput

0.407

High

567457

ASM
Sphingomyelin phosphodiesterase

2

0

High-throughput

0.328

High

1167560

ZPBP2
Zona pellucida-binding protein 2

2

0

High-throughput

0.328

High

1354369

RXLT1
Ribitol-5-phosphate xylosyltransferase 1

2

0

High-throughput

0.328

High

728890

ALS
Insulin-like growth factor-binding protein complex acid labile subunit

1

0

High-throughput

0.279

Low

856850

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.279

Low

885700

NXPH1
Neurexophilin-1

1

0

High-throughput

0.279

Low

968938

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1116863

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1126628

DB121
Beta-defensin 121

1

0

High-throughput

0.279

Low

1139335

LIPK
Lipase member K

1

0

High-throughput

0.279

Low

1162869

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1291449

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.279

Low

1303070

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.279

Low

1316360

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

1330796

DPEP2
Dipeptidase 2

1

0

High-throughput

0.279

Low

1332860

SPRNG
SREBP regulating gene protein

1

0

High-throughput

0.279

Low

637302

CATS
Cathepsin S

1

0

High-throughput

0.269

Low

541293

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

595961

HNF1A
Hepatocyte nuclear factor 1-alpha

1

0

Small-scale

0.249

Low

1101983

TECT1
Tectonic-1

1

0

High-throughput

0.249

Low

1231500

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1311709

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

2125

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024