Interactor 1: NOT2 (P06100)
General negative regulator of transcription subunit 2 (cell division cycle protein 36)
Gene: CDC36

Interactor 2: NOT1 (P25655)
General negative regulator of transcription subunit 1 (Cell division cycle protein 39)
Gene: CDC39

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 12215531, 24121231, 9463387, 7926748, 19707589, 16263706, 30948432, 35357307, 37968396, 20386698, 21669201, 18467557
Identification Methods two hybrid, tandem affinity purification, coimmunoprecipitation, pull down, affinity chromatography technology, biochemical, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5~Not1
Common GO terms GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000749 - response to pheromone triggering conjugation with cellular fusion
GO:0000932 - P-body
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 191
Sc

1 2108
+ Sc
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024