HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: HACD3 (Q9P035)
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1)
Gene: HACD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	25687571, 30300385
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1382 Hs			1 362
+	Rn
		88988 T2CB11_RAT (1-1382): 0: 1538: 94.87		D4ABI7_RAT (1-362): 2.92e-148: 424: 91.44
+	Rn
		88987 INSR_RAT (1-1382): 0: 1527: 94.44		D4ABI7_RAT (1-362): 2.92e-148: 424: 91.44
+	Hs
		435785 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		665673 EPHB2_HUMAN (521-1316): 3.12e-175: 551: 20.21		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		665537 EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		384007 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		385633 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		1081630 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00