HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: UTRN (P46939)
Utrophin (Dystrophin-related protein 1) (DRP-1)
Gene: UTRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 3433
+	Hs
		433640 LYN_HUMAN (1-509): 0: 582: 62.72		UTRN_HUMAN (1-3433): 0: 1138: 100.00
+	Hs
		433543 LYN_HUMAN (1-509): 0: 582: 62.72		DMD_HUMAN (28-2959): 8.71e-142: 503: 32.65
+	Hs
		411906 LCK_HUMAN (1-509): 0: 661: 100.00		DTNA_HUMAN (2841-3425): 1.78e-90: 315: 23.38
+	Hs
		434098 LYN_HUMAN (1-509): 0: 582: 62.72		DTNA_HUMAN (2841-3425): 1.78e-90: 315: 23.38
+	Hs
		297808 LYN_HUMAN (1-509): 0: 582: 62.72		K0754_HUMAN (1481-2942): 3.4e-79: 296: 14.12
+	Hs
		211480 SRC_HUMAN (20-507): 0: 586: 55.00		ACTN4_HUMAN (33-526): 5.25e-49: 193: 31.70
+	Hs
		164551 LCK_HUMAN (1-509): 0: 661: 100.00		SPTN2_HUMAN (778-2566): 3.09e-20: 101: 11.53
+	Hs
		411676 LCK_HUMAN (1-509): 0: 661: 100.00		SPTB2_HUMAN (1624-2926): 1.69e-18: 96.3: 9.49
+	Hs
		411889 LCK_HUMAN (1-509): 0: 661: 100.00		MACF1_HUMAN (1469-3290): 1.23e-15: 86.7: 9.59
+	Hs
		411682 LCK_HUMAN (1-509): 0: 661: 100.00		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33
+	Hs
		164555 LYN_HUMAN (1-509): 0: 582: 62.72		SPTN2_HUMAN (778-2566): 3.09e-20: 101: 11.53
+	Hs
		433700 LYN_HUMAN (1-509): 0: 582: 62.72		SPTB2_HUMAN (1624-2926): 1.69e-18: 96.3: 9.49
+	Hs
		434078 LYN_HUMAN (1-509): 0: 582: 62.72		MACF1_HUMAN (1469-3290): 1.23e-15: 86.7: 9.59
+	Hs
		433710 LYN_HUMAN (1-509): 0: 582: 62.72		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33