Protein: SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA)

Gene: SUCB1, SUCLA2
Organism: Homo sapiens
Interactions: 145
UniProt ID: Q9P2R7

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004775 - succinate-CoA ligase (ADP-forming) activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921464

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

2

8

High-throughput

0.811

High

279960

CISY
Citrate synthase, mitochondrial

2

4

High-throughput

0.754

High

856416

IF2M
Translation initiation factor IF-2, mitochondrial

3

5

High-throughput

0.667

High

1412611

CQ080
Mitochondrial nucleoid-associated protein 1

3

0

High-throughput

0.638

High

1139294

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

4

1

High-throughput

0.633

High

1247424

ATRAP
Type-1 angiotensin II receptor-associated protein

4

1

High-throughput

0.633

High

1388212

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

4

1

High-throughput

0.633

High

62007

GTPBA
GTP-binding protein 10

2

2

High-throughput

0.628

High

1111494

IQGA2
Ras GTPase-activating-like protein IQGAP2

2

1

High-throughput

0.628

High

1292243

LONP2
Lon protease homolog 2, peroxisomal

2

7

High-throughput

0.628

High

1401774

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

2

4

High-throughput

0.628

High

1310488

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

1

High-throughput

0.611

High

1401649

EFGM
Elongation factor G, mitochondrial

2

1

High-throughput

0.611

High

884719

SYHM
Histidine--tRNA ligase, mitochondrial

2

0

High-throughput

0.602

High

1211305

DNLZ
DNL-type zinc finger protein

2

0

High-throughput

0.602

High

1123467

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

243179

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

1087605

GRSF1
G-rich sequence factor 1

2

3

High-throughput

0.584

High

1162603

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

1380452

MAL2
Protein MAL2

2

0

High-throughput

0.580

High

897093

MAP2
Methionine aminopeptidase 2

2

1

High-throughput

0.574

High

1141610

OZF
Zinc finger protein OZF

2

1

High-throughput

0.574

High

1454818

MKLN1
Muskelin

2

2

High-throughput

0.574

High

1454814

TR10D
Tumor necrosis factor receptor superfamily member 10D

2

2

High-throughput

0.553

High

1454825

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

3

High-throughput

0.553

High

564488

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

1430262

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

127734

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

2

High-throughput

0.489

High

138328

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.489

High

325410

DIRA1
GTP-binding protein Di-Ras1

1

2

High-throughput

0.489

High

1417692

TX101
Testis-expressed protein 101

1

1

High-throughput

0.489

High

1420170

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

1

High-throughput

0.489

High

1454824

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

1

High-throughput

0.489

High

1454826

SAR1B
Small COPII coat GTPase SAR1B

1

6

High-throughput

0.489

High

61669

VWA8
von Willebrand factor A domain-containing protein 8

1

1

High-throughput

0.479

High

282120

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

287405

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

294465

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

401633

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

412739

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

471299

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

538042

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

649865

HEM0
5-aminolevulinate synthase, erythroid-specific, mitochondrial

1

1

Small-scale

0.479

High

786291

LONM
Lon protease homolog, mitochondrial

1

5

High-throughput

0.479

High

828998

MDHM
Malate dehydrogenase, mitochondrial

1

4

High-throughput

0.479

High

882933

EFTU
Elongation factor Tu, mitochondrial

1

5

High-throughput

0.479

High

1083790

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

1090579

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

1114527

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1117873

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.479

High

1142696

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

1207174

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1234557

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1273022

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

2

High-throughput

0.479

High

1335026

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1337245

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1367480

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1381763

FAKD4
FAST kinase domain-containing protein 4

1

2

High-throughput

0.479

High

1403462

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.479

High

1416575

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

2

High-throughput

0.479

High

1428760

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

2

High-throughput

0.479

High

1432645

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1433746

MTG2
Mitochondrial ribosome-associated GTPase 2

1

4

High-throughput

0.479

High

1436127

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

3

High-throughput

0.479

High

1438145

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

3

Small-scale

0.479

High

1451266

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1454815

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1454819

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.479

High

1119911

CKAP5
Cytoskeleton-associated protein 5

1

3

High-throughput

0.470

High

1454822

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.470

High

1386616

OPTN
Optineurin

1

1

High-throughput

0.470

High

66324

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

275126

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

351029

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

363962

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

519260

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

533029

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

842007

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852066

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

973332

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

985369

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.458

High

1015874

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

1024220

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1048744

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058340

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1386045

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.458

High

1388301

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1388444

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1412470

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1414110

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1415698

TR61B
tRNA

1

0

High-throughput

0.458

High

1418920

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1428824

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1431988

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1435819

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1450458

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1453967

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1454823

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

530496

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

653632

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

968017

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.445

High

1454827

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

4

High-throughput

0.445

High

1317012

FAM9B
Protein FAM9B

1

1

High-throughput

0.439

High

106782

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

122656

UBXN8
UBX domain-containing protein 8

1

2

High-throughput

0.437

High

386321

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.437

High

589925

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

696744

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

769401

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

831573

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

879567

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

908294

AFF1
AF4/FMR2 family member 1

1

2

High-throughput

0.437

High

1100478

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

1107297

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

1155853

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

1255912

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1380221

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.437

High

1386398

FAF2
FAS-associated factor 2

1

2

High-throughput

0.437

High

1397515

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

1429380

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.437

High

1434116

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1435397

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1454816

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1454817

TES
Testin

1

2

High-throughput

0.437

High

1454821

FND3A
Fibronectin type-III domain-containing protein 3A

1

2

High-throughput

0.437

High

1417164

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.426

High

1454820

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

1227619

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.407

High

238632

RAD21
Double-strand-break repair protein rad21 homolog

2

0

High-throughput

0.328

High

1388508

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.328

High

848949

MAGAB
Melanoma-associated antigen 11

2

0

High-throughput

0.316

High

1148956

SC23A
Protein transport protein Sec23A

2

0

High-throughput

0.316

High

571639

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.279

Low

946320

NXPH1
Neurexophilin-1

1

0

High-throughput

0.279

Low

1272755

MAEA
E3 ubiquitin-protein transferase MAEA

1

0

High-throughput

0.279

Low

1439205

AGO4
Protein argonaute-4

1

0

High-throughput

0.279

Low

1169513

LRC36
Leucine-rich repeat-containing protein 36

1

0

High-throughput

0.269

Low

869801

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.265

Low

1024906

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1106384

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

0

High-throughput

0.249

Low

1178438

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1253602

WDR87
WD repeat-containing protein 87

1

0

High-throughput

0.249

Low

1119344

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low

1324282

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.232

Low

1432214

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025