HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11546790, 15536091
Identification Methods	affinity chromatography technology, experimental interaction detection, coimmunoprecipitation
Interaction Type	physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030425 - dendrite GO:0048156 - tau protein binding GO:0048813 - dendrite morphogenesis
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 1827
+	Hs
		503258 SRC_HUMAN (1-537): 0: 598: 68.21		MTAP2_HUMAN (1-1827): 0: 638: 100.00
+	Hs
		411960 FYN_HUMAN (1-537): 0: 643: 100.00		TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72
+	Hs
		496189 SRC_HUMAN (1-537): 0: 598: 68.21		TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72
+	Hs
		412078 FYN_HUMAN (1-537): 0: 643: 100.00		KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84
+	Hs
		411566 LCK_HUMAN (40-535): 0: 551: 57.60		TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72
+	Hs
		64077 SRC_HUMAN (1-537): 0: 598: 68.21		L37A2_HUMAN (998-1689): 2.46e-24: 114: 9.44
+	Hs
		522847 SRC_HUMAN (1-537): 0: 598: 68.21		KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84
+	Hs
		337321 ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56		TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72
+	Hs
		523118 SRC_HUMAN (1-537): 0: 598: 68.21		CIC_HUMAN (26-1666): 2.83e-15: 84.3: 9.15
+	Hs
		434084 LYN_HUMAN (1-535): 0: 535: 54.48		SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82
+	Hs
		789101 FRK_HUMAN (77-529): 6.35e-176: 507: 52.26		KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84
+	Hs
		337387 ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56		KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84
+	Hs
		297808 LYN_HUMAN (1-535): 0: 535: 54.48		K0754_HUMAN (71-591): 3.89e-13: 77.5: 14.70
+	Hs
		996575 ITK_HUMAN (4-526): 5.88e-165: 483: 31.90		SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82