HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: IL3RA (P26951)
Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)
Gene: IL3RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 537 Hs			1 378
+	Hs
		412029 FYN_HUMAN (1-537): 0: 643: 100.00		CNTFR_HUMAN (41-303): 1.14e-40: 149: 14.49
+	Hs
		412037 FYN_HUMAN (1-537): 0: 643: 100.00		EPHA8_HUMAN (67-330): 2.75e-37: 145: 12.46
+	Hs
		412036 FYN_HUMAN (1-537): 0: 643: 100.00		EPHA3_HUMAN (60-329): 8.89e-36: 140: 11.00
+	Hs
		411991 FYN_HUMAN (1-537): 0: 643: 100.00		IL7RA_HUMAN (181-348): 2.43e-28: 117: 15.26
+	Hs
		522759 SRC_HUMAN (1-537): 0: 598: 68.21		EPOR_HUMAN (102-363): 4.2e-39: 147: 18.21
+	Hs
		522802 SRC_HUMAN (1-537): 0: 598: 68.21		EPHA3_HUMAN (60-329): 8.89e-36: 140: 11.00
+	Hs
		412051 FYN_HUMAN (1-537): 0: 643: 100.00		IL3RB_HUMAN (108-295): 4.67e-12: 69.5: 12.39
+	Mm
		411919 LCK_MOUSE (40-535): 0: 553: 57.20		CSF3R_MOUSE (98-307): 1.87e-34: 136: 18.34
+	Hs
		442875 HCK_HUMAN (1-535): 0: 548: 56.64		CSF3R_HUMAN (101-305): 7.42e-36: 140: 17.70
+	Hs
		433772 LYN_HUMAN (1-535): 0: 535: 54.48		EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50
+	Hs
		433567 LYN_HUMAN (1-535): 0: 535: 54.48		EPOR_HUMAN (102-363): 4.2e-39: 147: 18.21
+	Mm
		540265 LYN_MOUSE (1-535): 0: 535: 53.92		EPOR_MOUSE (102-363): 4.92e-39: 147: 18.35
+	Mm
		435879 HCK_MOUSE (1-535): 0: 542: 56.45		CSF3R_MOUSE (98-307): 1.87e-34: 136: 18.34
+	Hs
		433602 LYN_HUMAN (1-535): 0: 535: 54.48		EPHA3_HUMAN (60-329): 8.89e-36: 140: 11.00
+	Hs
		433961 LYN_HUMAN (1-535): 0: 535: 54.48		CSF3R_HUMAN (101-305): 7.42e-36: 140: 17.70
+	Hs
		789068 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50
+	Hs
		337354 ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56		CNTFR_HUMAN (41-303): 1.14e-40: 149: 14.49
+	Hs
		337359 ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56		EPHA3_HUMAN (60-329): 8.89e-36: 140: 11.00
+	Hs
		442787 HCK_HUMAN (1-535): 0: 548: 56.64		IL6RB_HUMAN (35-344): 3.57e-12: 69.8: 12.81
+	Hs
		433612 LYN_HUMAN (1-535): 0: 535: 54.48		IL3RB_HUMAN (108-295): 4.67e-12: 69.5: 12.39