HitPredict

Interactor 1: KAPB (P06245)
cAMP-dependent protein kinase type 2 (PKA 2) (EC 2.7.11.11)
Gene: TPK2

Interactor 2: HSP60 (P19882)
Heat shock protein 60, mitochondrial (CPN60) (P66) (Stimulator factor I 66 kDa component)
Gene: HSP60

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 16429126
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 380 Sc			1 572
+	Dm
		137757 AKT1_DROME (4-380): 1.68e-148: 434: 33.25		CH60A_DROME (1-553): 0: 544: 55.96
+	Sc
		412651 KAPA_YEAST (5-380): 1.15e-151: 435: 66.49		HSP60_YEAST (1-548): 0: 542: 100.00
+	Hs
		681999 AKT1_HUMAN (4-375): 3.08e-149: 432: 34.75		TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04
+	Hs
		609692 KAPCG_HUMAN (56-380): 2.87e-147: 422: 48.62		TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04
+	Hs
		500182 KS6B2_HUMAN (56-380): 6.79e-141: 411: 37.61		CH60_HUMAN (4-556): 5.37e-180: 521: 54.38
+	Hs
		681735 AKT1_HUMAN (4-375): 3.08e-149: 432: 34.75		TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84
+	Hs
		681738 AKT1_HUMAN (4-375): 3.08e-149: 432: 34.75		TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46
+	Hs
		568585 KAPCA_HUMAN (35-380): 9.1e-149: 426: 47.69		TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84
+	Hs
		1306721 KS6B2_HUMAN (56-380): 6.79e-141: 411: 37.61		TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04
+	Hs
		609651 KAPCG_HUMAN (56-380): 2.87e-147: 422: 48.62		TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84
+	Hs
		609652 KAPCG_HUMAN (56-380): 2.87e-147: 422: 48.62		TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46
+	Hs
		821449 KS6B2_HUMAN (56-380): 6.79e-141: 411: 37.61		TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84
+	Hs
		826928 KS6B2_HUMAN (56-380): 6.79e-141: 411: 37.61		TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46
+	Sc
		520575 YPK1_YEAST (66-357): 3.82e-80: 260: 44.41		HSP60_YEAST (1-548): 0: 542: 100.00
+	Hs
		1306691 SGK2_HUMAN (69-367): 1.09e-79: 250: 42.76		TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04
+	Hs
		821419 SGK2_HUMAN (69-367): 1.09e-79: 250: 42.76		TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84
+	Hs
		826897 SGK2_HUMAN (69-367): 1.09e-79: 250: 42.76		TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46